Temcox 120 mg (Tablet)

Unit Price: ৳ 13.00 (2 x 10: ৳ 260.00)
Strip Price: ৳ 130.00

Medicine Details

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Potent COX-2 specific inhibitor
  • Decreases pain, inflammation, and fever
  • Selective inhibition of COX-2
  • Did not inhibit gastric prostaglandin synthesis

DosageAndAdministration

  • Initial dose of 30 mg once daily for OA
  • Increased dose of 60 mg once daily for insufficient relief
  • 90 mg once daily for RA and ankylosing spondylitis
  • 120 mg once daily for acute gouty arthritis
  • 90 mg once daily for postoperative dental surgery pain, limited to a maximum of 3 days

Interaction

  • Increase in prothrombin time with oral anticoagulants
  • Reduction in the effect of diuretics and antihypertensive drugs
  • Usage with low-dose acetylsalicylic acid is possible
  • Potential increase in nephrotoxic effect of ciclosporin or tacrolimus
  • Decrease in lithium renal excretion, leading to increased plasma levels

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or GI bleeding
  • History of allergic-type reactions to NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance <30 ml/min
  • Children and adolescents under 16 years of age
  • Inflammatory bowel disease
  • Congestive heart failure, hypertension, established cardiovascular diseases

SideEffects

  • Palpitations
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Atrial fibrillation
  • Chest pain
  • Anxiety
  • Myalgia
  • Arthralgia
  • Confusion
  • Hallucinations

PregnancyAndLactation

  • Not recommended in women attempting to conceive
  • Not recommended for breastfeeding mothers

PrecautionsAndWarnings

  • Caution with patients at risk of gastrointestinal complications
  • Careful consideration for patients with cardiovascular risk factors
  • Monitoring of renal function
  • Exercise caution in patients with cardiac failure, edema, liver dysfunction
  • Monitoring and discontinuation in case of hypersensitivity or hepatic insufficiency
  • Caution when co-administering with warfarin or other oral anticoagulants

OverdoseEffects

  • Single doses up to 500 mg did not result in significant toxicity
  • Usual supportive measures recommended in case of overdose

TherapeuticClass

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

StorageConditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

ChemicalStructure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure: Image available

CommonQuestionsAboutTemcox120MgTablet

  • Selective COX-2 inhibitor
  • Indicated for Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis
  • Duration of effect is 20-24 hours
  • Onset of action within 1-2 hours
  • Pregnancy warnings
  • Not habit forming
  • Breastfeeding warnings
  • Unsafe with alcohol
  • May affect alertness and kidney function
  • Caution needed in liver disease
  • Quick Tips for usage

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