Riox 60 mg (Tablet)

Unit Price: ৳ 7.00 (2 x 10: ৳ 140.00)
Strip Price: ৳ 70.00

Medicine Details

Product Title

  • Riox 60 mg Tablet

Categories

  • Pain Relief
  • Anti-inflammatory
  • Medication

Description

  • Symptomatic relief for Osteoarthritis (OA)
  • Symptomatic relief for Rheumatoid arthritis (RA)
  • Symptomatic relief for Ankylosing spondylitis
  • Symptomatic relief for acute gouty arthritis pain and signs of inflammation
  • Short-term treatment of moderate pain associated with dental surgery
  • Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor

Dosage & Administration

  • Recommended dose for Osteoarthritis: 30 mg once daily, may increase to 60 mg for some patients
  • Recommended dose for Rheumatoid arthritis: 90 mg once daily
  • Recommended dose for Ankylosing spondylitis: 90 mg once daily
  • Recommended dose for Acute gouty arthritis: 120 mg once daily for 8 days
  • Recommended dose for postoperative dental surgery pain: 90 mg once daily, limited to a maximum of 3 days
  • Usage caution for patients with cardiovascular risks

Interactions

  • Interaction with oral anticoagulants leading to an increase in prothrombin time
  • Potential reduction in the effect of diuretics and other antihypertensive drugs
  • Concomitant use with low-dose acetylsalicylic acid for cardiovascular prophylaxis
  • Potential interaction with ciclosporin, tacrolimus, and lithium
  • Advised to take without regards to meals

Contraindications

  • Hypersensitivity to the active substance or excipients
  • Active peptic ulceration or active gastrointestinal (GI) bleeding
  • History of bronchospasm, angioneurotic edema, or allergic-type reactions to NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min
  • Inflammatory bowel disease, congestive heart failure, uncontrolled hypertension

Side Effects

  • Palpitation, fatigue, influenza-like symptoms
  • Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
  • Atrial fibrillation, chest pain, flushing, cough, dyspnea, epistaxis
  • Anxiety, impaired mental acuity, paraesthesia, myalgia, arthralgia
  • Rare cases of confusion and hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Excretion in lactating rats, breastfeeding while using is not advised

Precautions & Warnings

  • Caution for patients at risk of gastrointestinal complications with NSAIDs
  • Consideration for patients with significant cardiovascular risk factors
  • Monitoring of renal function due to prostaglandin inhibition
  • Exercise caution in patients with history of cardiac failure, left ventricular dysfunction, or hypertension
  • Monitoring and potential discontinuation upon signs of hepatic insufficiency

Overdose Effects

  • No significant toxicity observed with single or multiple doses up to specified levels
  • Supportive measures in the event of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store below 30°C, protect from light & moisture, keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S

Common Questions & Answers

  • Riox 60 mg Tablet is a selective COX-2 inhibitor
  • Indicated for the symptomatic relief of Osteoarthritis (OA), Rheumatoid arthritis (RA), Ankylosing spondylitis
  • Duration of effect: 20-24 hours
  • Onset of action: 1-2 hours, faster if taken without food
  • Warnings about pregnancy and breastfeeding
  • No habit forming tendencies reported
  • Unsafe to consume with alcohol, may affect alertness
  • Caution in patients with kidney and liver disease
  • Quick tips for usage and precautions

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