Riox 90 mg (Tablet)

Unit Price: ৳ 12.00 (2 x 10: ৳ 240.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Etoricoxib
Company Unimed unihealth pharmaceuticals ltd
Also available as
Riox 60 mg tablet Riox 120 mg tablet

Title and Categories

  • Riox 90 mg Tablet
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Indications

  • Symptomatic relief of Osteoarthritis (OA)
  • Rheumatoid arthritis (RA)
  • Ankylosing spondylitis
  • Pain and signs of inflammation associated with acute gouty arthritis
  • Short-term treatment of moderate pain associated with dental surgery

Dosage & Administration

  • Recommended dose for Osteoarthritis: 30 mg once daily, may be increased to 60 mg once daily if necessary
  • Recommended dose for Rheumatoid arthritis: 90 mg once daily
  • Recommended dose for Ankylosing spondylitis: 90 mg once daily
  • Recommended dose for Acute gouty arthritis: 120 mg once daily for 8 days
  • Recommended dose for Postoperative dental surgery pain: 90 mg once daily, limited to a maximum of 3 days
  • Patients may require additional postoperative analgesia
  • Shortest duration possible and lowest effective daily dose should be used to minimize cardiovascular risks
  • Patients' need for symptomatic relief and response to therapy should be re-evaluated periodically

Interaction with other drugs

  • May increase prothrombin time in subjects stabilized on chronic warfarin therapy
  • May reduce the effect of diuretics and other antihypertensive drugs
  • Can be used concomitantly with low-dose acetylsalicylic acid used for cardiovascular prophylaxis
  • Coadministration with ciclosporin or tacrolimus may increase the nephrotoxic effect
  • Decreases lithium renal excretion and increases lithium plasma levels

Contraindications

  • Hypersensitivity to the active substance or to any of the excipients
  • Active peptic ulceration or active gastrointestinal (GI) bleeding
  • History of allergic-type reactions after taking acetylsalicylic acid or NSAIDs including COX-2 inhibitors
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance below 30 ml/min
  • Children and adolescents under 16 years of age
  • Inflammatory bowel disease
  • Congestive heart failure (NYHA ll-IV)
  • Uncontrolled hypertension
  • Established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Appetite and weight change
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia and arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Excreted in the milk of lactating rats
  • Women who use the product must not breastfeed

Precautions & Warnings

  • Caution advised with treatment of patients most at risk of developing gastrointestinal complications with NSAIDs
  • Patients with significant risk factors for cardiovascular events should be treated with caution
  • May cause reduction in prostaglandin formation and impair renal function
  • Caution in patients with a history of cardiac failure, left ventricular dysfunction, or hypertension, and in patients with pre-existing edema
  • Monitoring of renal function in high-risk patients is recommended
  • Monitor for signs of liver dysfunction and hypersensitivity reactions
  • May mask fever and other signs of inflammation
  • Caution when co-administering with warfarin or other oral anticoagulants

Overdose Effects

  • Administration of single doses up to 500 mg and multiple doses up to 150 mg/day did not result in significant toxicity
  • Usual supportive measures should be employed in case of overdose

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C18H15ClN2O2S
  • Chemical Structure: Image of chemical structure provided

Duration of Effect

20-24 hours

Onset of Action

1-2 hours, faster if taken without food

Pregnancy warnings

Consult doctor before use

Habit forming

No habit-forming tendencies reported

Breastfeeding warnings

Not recommended, consult doctor

Safe with alcohol

Unsafe to consume with alcohol

Safe to drive

May affect patient's alertness, avoid driving

Kidney function

Caution in patients with kidney disease, dose adjustment may be needed

Liver function

Caution in patients with liver disease, dose adjustment may be needed

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