Riox 120 mg (Tablet)
Unit Price: ৳ 14.00 (2 x 10: ৳ 280.00)
Strip Price: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Etoricoxib |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Product Title
- Riox 120 mg Tablet
Categories
- Medicine
- Healthcare
- Pain Management
Indications
- Symptomatic relief of Osteoarthritis (OA)
- Rheumatoid arthritis (RA)
- Ankylosing spondylitis
- Pain and signs of inflammation associated with acute gouty arthritis
- Short-term treatment of moderate pain associated with dental surgery
Pharmacology
- Potent, orally active cyclooxygenase-2 (COX-2) specific inhibitor
- Selective inhibition of COX-2 decreases clinical signs and symptoms with decreased potential for GI toxicity and effects on platelet aggregation
- Dose-dependent inhibition of COX-2 without inhibition of COX-1 at doses up to 150 mg daily
Dosage & Administration
- Recommended doses for different conditions and patient groups
- Shortest duration possible and lowest effective daily dose should be used
- Need for symptomatic relief and response to therapy should be re-evaluated periodically
Interactions
- Interactions with oral anticoagulants, diuretics, ACE inhibitors, Angiotensin II Antagonists, acetylsalicylic acid, ciclosporin, tacrolimus, and lithium
Contraindications
- Hypersensitivity to the active substance or excipients
- Active peptic ulceration or active GI bleeding
- Pregnancy and lactation
- Severe hepatic dysfunction
- Estimated renal creatinine clearance <30 ml/min
- Children and adolescents under 16 years of age
- Inflammatory bowel disease
- Congestive heart failure, hypertension, ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease
Side Effects
- Palpitation, fatigue, influenza-like symptoms, ecchymosis
- Dry mouth, taste disturbance, mouth ulcer, appetite and weight change
- Atrial fibrillation, transient ischaemic attack, chest pain, flushing, cough, dyspnoea
- Anxiety, mental acuity impaired, paraesthesia, electrolyte disturbance, myalgia and arthralgia
- Confusion and hallucinations (very rarely)
Pregnancy & Lactation
- Not recommended in women attempting to conceive
- Excretion in rat milk, thus not recommended for breastfeeding women
Precautions & Warnings
- Caution in patients at risk of developing GI complication with NSAIDs
- Treatment for patients with significant risk factors for cardiovascular events after careful consideration
- Monitoring of renal function in patients at risk
- Caution in patients with a history of cardiac failure, left ventricular dysfunction, hypertension, pre-existing edema, and symptoms suggesting liver dysfunction
- Discontinuation at the first appearance of hypersensitivity signs
- Caution when co-administering with warfarin or other oral anticoagulants
Overdose Effects
- Administration of single doses up to 500 mg and multiple doses up to 150 mg/day for 21 days did not result in significant toxicity
- Employment of usual supportive measures and clinical monitoring in case of overdose
Therapeutic Class
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store at a temperature below 30°C, protect from light & moisture, keep out of reach of children
Chemical Structure
- Molecular Formula: C18H15ClN2O2S
- Chemical Structure Image URL: https://medex.com.bd/storage/res/g-res-446-etoricoxib-chemical-structure-nEkDifKyFxQ9fjJEG7TQ.svg
Commonly Asked Questions
- Information about the use, duration of effect, onset of action, pregnancy warnings, habit forming tendencies, breast-feeding warnings, safety with alcohol, driving, kidney & liver function, and quick tips for patients
Other Information
- Take without regards to meals
Health Conditions Excluded
- Hypersensitivity, active peptic ulceration or GI bleeding, pregnancy, lactation, severe hepatic dysfunction, estimated renal creatinine clearance <30 ml/min, children and adolescents under 16 years of age, inflammatory bowel disease, congestive heart failure, hypertension, ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease