Fenobate 200 mg (Capsule)
Unit Price: ৳ 7.00 (5 x 6: ৳ 210.00)
Strip Price: ৳ 42.00
Medicine Details
Category | Details |
---|---|
Generic | Fenofibrate |
Company | Renata limited |
Indications
- Hyperlipidemias type lla
- Hyperlipidemias type llb
- Hyperlipidemias type III
- Hyperlipidemias type IV
- Hyperlipidemias type V
- Non-responsive to diet
Pharmacology
- Fibric acid derivative
- Rapid hydrolysis
- Pharmacologically active form
- Reductions in cholesterol levels
- Increases in HDL levels
- Reduces serum uric acid levels
Dosage & Administration
- Initial dose 200mg per day for hypercholesterolemia
- Initial dose 67 to 200mg per day for hypertriglyceridemia
- Individualized dosing
- Optimized bioavailability with meal intake
Interaction
- Potentiates anticoagulant effects of warfarin
- Improves glucose tolerance when administered with antidiabetic drugs
- Increases nephrotoxicity of cyclosporine
- Cautions with HMG-CoA reductase inhibitors
- Well tolerated with low-dose statins
Contraindications
- Hypersensitivity to Fenofibrate
- Severe renal or hepatic impairment
- Existing gall bladder disease
- Breastfeeding
- Photosensitivity to ketoprofen
Side Effects
- Gastro-intestinal issues
- Pruritus
- Urticaria
- Impotence
- Headache
- Dizziness
- Fatigue
- Hair loss
- Myotoxicity
Pregnancy & Lactation
- Not recommended for pregnant women
Precautions & Warnings
- Special care needed in patients with renal disease
- Progressive increases in serum creatinine concentration may result in myotoxicity
- Discontinue if myotoxicity suspected
- Liver function tests recommended every 3 months
Overdose Effects
- No specific treatment for overdose
- General supportive care indicated
- Hemodialysis not considered due to high plasma protein binding
Therapeutic Class
- Fibrates
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children