Esom-E 20 mg (Tablet (Enteric Coated))

Product Title

• Esom-E 20 mg Tablet

Category

• Medicine
• Gastrointestinal Health

Indications

• Relief from chronic heartburn symptoms
• Healing of erosive esophagitis
• Maintenance of healing of erosive esophagitis
• Eradication of Helicobacter pylori infection
• Treatment of Zollinger-Ellison Syndrome
• Acid related Dyspepsia
• Duodenal and Gastric ulcers

Dosage Forms

• Tablet
• Capsule
• Oral Suspension
• IV Injection
• IV Infusion

Dosage

• 20 mg or 40 mg once daily for 4-8 weeks for healing of erosive esophagitis
• 20 mg once daily for maintenance of healing of erosive esophagitis
• 20 mg once daily for symptomatic GERD
• Triple Therapy for Helicobacter pylori eradication
• 20-80 mg once daily for Zollinger-Ellison Syndrome
• 20-40 mg once daily for acid-related Dyspepsia
• 20 mg once daily for 2-4 weeks for Duodenal ulcer
• 20-40 mg once daily for 4-8 weeks for Gastric ulcer
• IV dosages for adult and pediatric patients

Administration

• Tablet or capsule should be swallowed whole and taken one hour before a meal
• Oral Suspension and IV Injection administration guidelines

Mode of Action

• Proton pump inhibitor that suppresses gastric acid secretion
• Absorption, Distribution, Metabolism, and Excretion details

Interaction

• Metabolized by liver enzymes CYP2C19 and CYP3A4
• Potential interactions with certain drugs
• Interference with CYP2C19 enzyme
• Effects of combination therapy with Clarithromycin

Contraindications

• Known hypersensitivity to any of the formulation

Side Effects

• Headache
• Diarrhea
• Nausea
• Flatulence
• Abdominal pain
• Constipation
• Dry mouth

Pregnancy & Lactation

• No adequate and well-controlled studies in pregnant women
• No teratogenic effects observed in animal studies
• Excretion in milk not studied
• Breastfeeding discontinuation if essential

Precautions & Warnings

• Symptomatic response does not rule out gastric malignancy
• Instructions for patients regarding capsule intake and use of antacids

Special Populations

• Paediatric Use safety and effectiveness not established
• No overall differences in safety and efficacy observed in geriatric use
• No dosage adjustment recommended for mild to moderate hepatic insufficiency
• No alteration in Pharmacokinetics in renal impairment

Overdose Effects

• Lethal effects observed in rats at high doses
• Potential signs of acute toxicity
• No specific antidote known
• Symptomatic and supportive treatment advised

Storage Conditions

• Store at a temperature not exceeding 30°C in a dry place
• Protect from light and moisture
• Keep out of reach of children

Chemical Structure

• Molecular Formula: C17H19N3O3S
• Chemical Structure Image

Commonly Asked Questions

• Definition and usage of Esom-E 20 mg Tablet
• Common side effects and side effects comparison for short-term and long-term use
• Pregnancy and breastfeeding related information
• Onset time of action
• Quick tips for usage

Medication Caution

• Antacids may be used while taking Esom-E

Compound Summary

• Molecular formula description

Overdose Treatment

• Supportive and symptomatic treatment advised

Compound Image

• Chemical structure image of Esomeprazole

IV Dosage Guidelines

• Specific dosages for adult and pediatric patients for various conditions

Medication Precautions

• Instruction for patients with difficulty swallowing capsules

Special Population Use

• Use in pediatric, geriatric, hepatic, and renal impaired patients

Common Question Topics

• Esom-E 20 mg Tablet definition and usage
• Side effects
• Pregnancy and breastfeeding use
• Onset of action
• Quick tips

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