Esomenta 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (7 x 10: ৳ 490.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Jenphar bangladesh ltd
Also available as
Esomenta 40 mg capsule

Title and Categories

  • Esomenta 20 mg Capsule

Indications

  • Relief from chronic heartburn and GERD symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Zollinger-Ellison Syndrome
  • Acid related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Enteric-coated pellet formulation
  • Metabolized in the liver by CYP enzymes
  • Minimal urine excretion

Dosage

  • Oral dosage form for various conditions
  • 20 mg or 40 mg Once Daily for 4-8 Weeks for erosive esophagitis
  • 20 mg Once Daily for maintenance of erosive esophagitis
  • 20 mg Once Daily for symptomatic GERD
  • Triple Therapy for Helicobacter Pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for Acid-related Dyspepsia
  • 20 mg once daily for 2-4 weeks for Duodenal ulcer and 4-8 weeks for Gastric ulcer
  • IV Injection and Infusion dosage for various conditions

Administration

  • Tablet or capsule to be swallowed whole
  • Oral suspension preparation and administration
  • IV injection preparation and administration

Interaction

  • Extensively metabolized by CYP2C19 and CYP3A4
  • Unlikely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, 3A4
  • Potential interference with CYP2C19 and gastric pH-dependent drugs
  • No clinically significant interactions with specific drugs

Contraindications

  • Known hypersensitivity to the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies showed no teratogenic effects
  • No information on excretion in milk
  • Breastfeeding discontinuation if essential

Precautions & Warnings

  • Symptomatic response does not rule out gastric malignancy
  • Guidance for patients with difficulty swallowing capsules
  • Can be taken with antacids
  • Dosage adjustment for hepatic insufficiency

Special Populations Use

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy in the elderly
  • No dosage adjustment for mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics for renal impairment

Overdose Effects

  • Lethal at high doses in rats
  • Reduced motor activity and respiratory frequency
  • Supportive and symptomatic treatment recommended

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry and protected from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Commonly Asked Questions

  • PPI for reducing stomach acid production
  • Used for GERD, ulcers, and excessive stomach acid
  • Common side effects and lack of difference in short-term and long-term use
  • Untested safety in pregnancy and breastfeeding
  • Quick Tips for usage and side effect management

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