Zenifol Plus 200 mg+400 mcg (Tablet)

Unit Price: ৳ 0.39 (1 x 45: ৳ 17.55)

Medicine Details

Indications

  • Prophylaxis and treatment of Iron deficiency anaemia in pregnancy.
  • Prevention of megaloblastic anaemia of pregnancy.

Pharmacology

  • Iron is essential for haemoglobin formation
  • Iron deficiency anaemia is often caused by chronic haemorrhage, nutritional deficiency, pregnancy, parasite infestation, or malabsorption of iron
  • Deficiency of Folic acid during pregnancy can cause megaloblastic anaemia
  • Folic acid and ferrous fumerate combination avoids complications of rapid red blood cell production

Dosage & Administration

  • One tablet daily for adults
  • In pregnancy, recommended to start at first antenatal consultation and continue for 3 months after delivery
  • Preferably taken before meals, or after meals if there are gastrointestinal disturbances

Interaction

  • Absorption of iron salts and tetracycline is diminished when taken concomitantly by mouth
  • Iron salts absorption is decreased with antacids or when taken with tea
  • Iron salts may reduce the effects of penicillamine
  • Co-trimoxazole may inhibit megaloblastic haemopoiesis
  • Administration of folate may reduce serum anticonvulsant levels

Contraindications

  • Contraindicated in pernicious anaemia and anaemia other than those due to iron deficiency
  • Absorption inhibited by Magnesium trisillicate and Antacid containing carbonate

Side Effects

  • Nausea
  • Vomiting
  • Gastrointestinal symptoms
  • Constipation
  • Diarrhea

Precautions & Warnings

  • Administration during the first trimester of pregnancy may be undesirable
  • Investigate further if anaemia develops despite prophylaxis
  • Care needed when treating patients with peptic ulcer

Overdose Effects

  • Gastric lavage if possible within four hours of the overdosage
  • Symptomatic treatment as necessary
  • Chelating agent like desferrioxamine to eliminate excess free iron

Therapeutic Class

  • Iron & Vitamin Combined preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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