Esomep 40 mg/vial (IV Injection)

40 mg vial: ৳ 90.27

Medicine Details

Category Details
Generic Esomeprazole
Company Aci limited
Also available as
Esomep 20 mg tablet Esomep 40 mg tablet Esomep 20 mg capsule Esomep 40 mg capsule

Title

Esomep 40 mg/vial Injection

Categories

  • Medicine
  • Gastroenterology
  • Pharmacology
  • Proton Pump Inhibitor
  • Acid Control
  • Gastric Health

Description

Esomep 40 mg/vial Injection is a proton pump inhibitor (PPI) indicated for various conditions including chronic heartburn, GERD, erosive esophagitis, H. pylori infection eradication, Zollinger-Ellison Syndrome, Acid-related Dyspepsia, Duodenal and Gastric ulcers.

Dosage

  • 20 mg or 40 mg Once Daily for Erosive Esophagitis Healing
  • 20 mg Once Daily for Maintenance of Erosive Esophagitis Healing
  • 20 mg Once Daily for Symptomatic GERD
  • Triple Therapy for H. pylori Eradication: Esomeprazole 40 mg Once Daily, Amoxicillin 1000 mg Twice Daily, Clarithromycin 500 mg Twice Daily for 10 Days
  • 20-80 mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40 mg Once Daily for Acid-related Dyspepsia for 2-4 Weeks
  • 20 mg Once Daily for 2-4 Weeks for Duodenal Ulcer, 20-40 mg Once Daily for 4-8 Weeks for Gastric Ulcer

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be taken with water and consumed within 30 minutes
  • IV Injection: Esomep 40mg should be injected intravenously over a period of at least 3 minutes

Interaction

  • Esomep is not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
  • No clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin
  • May interfere with the absorption of drugs where gastric pH is important for bioavailability
  • Co-administration with clarithromycin may result in increased plasma levels of Esomep and 14-hydroxyclarithromycin

Contraindications

  • Known hypersensitivity to any of the formulation

Side effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal Pain
  • Constipation
  • Dry Mouth

Pregnancy lactation

No adequate and well-controlled studies in pregnant women. The excretion of esomeprazole in milk has not been studied. Breastfeeding should be discontinued if esomeprazole is considered essential

Precautions warnings

  • Symptomatic response to therapy with Esomep does not preclude the presence of gastric malignancy
  • Esomep capsules should be taken at least one hour before meals
  • Antacids may be used while taking Esomep

Special populations

  • Safety and effectiveness in paediatric patients have not been established
  • No overall differences in safety and efficacy have been observed between the elderly and younger individuals
  • No dosage adjustment is recommended for patients with mild to moderate hepatic insufficiency
  • The pharmacokinetics of Esomep in patients with renal impairment are not expected to be altered

Overdose effects

  • Reduced motor activity
  • Changes in respiratory frequency
  • Tremor
  • Ataxia
  • Intermittent clonic convulsions
  • Symptomatic and supportive treatment in case of overdosage

Storage conditions

Store at a temperature not exceeding 30°C in a dry place. Protect from light and moisture. Keep out of reach of children

Chemical structure

  • Molecular formula: C17H19N3O3S
  • Chemical structure image url: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg

Common questions

  • What is Esomep 40 mg/vial Injection?: Esomep 40 mg/vial Injection is a proton pump inhibitor (PPI). PPIs work by reducing the amount of acid produced in the stomach. Esomep 40 mg/vial Injection is used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions that involve too much stomach acid.
  • What is Esomep 40 mg/vial Injection used for?: Esomep 40 mg/vial Injection has multiple uses. It eases heartburn and relieves GERD symptoms. It also aids in healing erosive esophagitis, a condition caused by stomach acid damaging the esophagus lining. Additionally, Esomep 40 mg/vial Injection effectively prevents erosive esophagitis recurrence.
  • What are the side effects of Esomep 40 mg/vial Injection?: Esomep 40 mg/vial Injection may cause common side effects like headaches, diarrhea, nausea, gas, stomach pain, constipation, and dry mouth. There aren't any differences in the types of side effects between long-term (up to 12 months) and short-term use.
  • Can I take Esomep 40 mg/vial Injection if I am pregnant or breastfeeding?: Esomep 40 mg/vial Injection doesn't have any side-effects if you are pregnant or breastfeeding. You still should talk to your doctor about the risks and benefits of taking Esomep 40 mg/vial Injection.
  • How long does it take for Esomep 40 mg/vial Injection to work?: Esomep 40 mg/vial Injection usually starts to work within a few hours of taking it.
  • Quick Tips:
    • Esomep 40 mg/vial Injection is a well-tolerated medicine and provides relief for a long time
    • Avoid eating late at night or before bedtime
    • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away
    • Long-term use of Esomep 40 mg/vial Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor
    • Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem

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