Esomep 40 mg/vial (IV Injection)
40 mg vial: ৳ 90.27
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Aci limited |
Also available as |
Title
Esomep 40 mg/vial Injection
Categories
- Medicine
- Gastroenterology
- Pharmacology
- Proton Pump Inhibitor
- Acid Control
- Gastric Health
Description
Esomep 40 mg/vial Injection is a proton pump inhibitor (PPI) indicated for various conditions including chronic heartburn, GERD, erosive esophagitis, H. pylori infection eradication, Zollinger-Ellison Syndrome, Acid-related Dyspepsia, Duodenal and Gastric ulcers.
Dosage
- 20 mg or 40 mg Once Daily for Erosive Esophagitis Healing
- 20 mg Once Daily for Maintenance of Erosive Esophagitis Healing
- 20 mg Once Daily for Symptomatic GERD
- Triple Therapy for H. pylori Eradication: Esomeprazole 40 mg Once Daily, Amoxicillin 1000 mg Twice Daily, Clarithromycin 500 mg Twice Daily for 10 Days
- 20-80 mg Once Daily for Zollinger-Ellison Syndrome
- 20-40 mg Once Daily for Acid-related Dyspepsia for 2-4 Weeks
- 20 mg Once Daily for 2-4 Weeks for Duodenal Ulcer, 20-40 mg Once Daily for 4-8 Weeks for Gastric Ulcer
Administration
- Tablet or capsule should be swallowed whole and taken one hour before a meal
- Oral Suspension should be taken with water and consumed within 30 minutes
- IV Injection: Esomep 40mg should be injected intravenously over a period of at least 3 minutes
Interaction
- Esomep is not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
- No clinically significant interactions with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin
- May interfere with the absorption of drugs where gastric pH is important for bioavailability
- Co-administration with clarithromycin may result in increased plasma levels of Esomep and 14-hydroxyclarithromycin
Contraindications
- Known hypersensitivity to any of the formulation
Side effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal Pain
- Constipation
- Dry Mouth
Pregnancy lactation
No adequate and well-controlled studies in pregnant women. The excretion of esomeprazole in milk has not been studied. Breastfeeding should be discontinued if esomeprazole is considered essential
Precautions warnings
- Symptomatic response to therapy with Esomep does not preclude the presence of gastric malignancy
- Esomep capsules should be taken at least one hour before meals
- Antacids may be used while taking Esomep
Special populations
- Safety and effectiveness in paediatric patients have not been established
- No overall differences in safety and efficacy have been observed between the elderly and younger individuals
- No dosage adjustment is recommended for patients with mild to moderate hepatic insufficiency
- The pharmacokinetics of Esomep in patients with renal impairment are not expected to be altered
Overdose effects
- Reduced motor activity
- Changes in respiratory frequency
- Tremor
- Ataxia
- Intermittent clonic convulsions
- Symptomatic and supportive treatment in case of overdosage
Storage conditions
Store at a temperature not exceeding 30°C in a dry place. Protect from light and moisture. Keep out of reach of children
Chemical structure
- Molecular formula: C17H19N3O3S
- Chemical structure image url: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg
Common questions
- What is Esomep 40 mg/vial Injection?: Esomep 40 mg/vial Injection is a proton pump inhibitor (PPI). PPIs work by reducing the amount of acid produced in the stomach. Esomep 40 mg/vial Injection is used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions that involve too much stomach acid.
- What is Esomep 40 mg/vial Injection used for?: Esomep 40 mg/vial Injection has multiple uses. It eases heartburn and relieves GERD symptoms. It also aids in healing erosive esophagitis, a condition caused by stomach acid damaging the esophagus lining. Additionally, Esomep 40 mg/vial Injection effectively prevents erosive esophagitis recurrence.
- What are the side effects of Esomep 40 mg/vial Injection?: Esomep 40 mg/vial Injection may cause common side effects like headaches, diarrhea, nausea, gas, stomach pain, constipation, and dry mouth. There aren't any differences in the types of side effects between long-term (up to 12 months) and short-term use.
- Can I take Esomep 40 mg/vial Injection if I am pregnant or breastfeeding?: Esomep 40 mg/vial Injection doesn't have any side-effects if you are pregnant or breastfeeding. You still should talk to your doctor about the risks and benefits of taking Esomep 40 mg/vial Injection.
- How long does it take for Esomep 40 mg/vial Injection to work?: Esomep 40 mg/vial Injection usually starts to work within a few hours of taking it.
- Quick Tips:
- Esomep 40 mg/vial Injection is a well-tolerated medicine and provides relief for a long time
- Avoid eating late at night or before bedtime
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away
- Long-term use of Esomep 40 mg/vial Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem
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