Esonix 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 10.00 (4 x 14: ৳ 560.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Esomeprazole
Company Incepta pharmaceuticals ltd
Also available as
Esonix 20 mg tablet Esonix 20 mg capsule Esonix 40 mg capsule Esonix 40 mg injection Esonix 20 mg powder Esonix 20 mg injection

Indications

  • Relieve chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment for Zollinger-Ellison Syndrome
  • Treatment for acid-related Dyspepsia
  • Treatment for Duodenal and Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Peak plasma levels occur at approximately 1.5 hours after oral administration

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Dosage for healing of erosive esophagitis
  • Dosage for symptomatic GERD
  • Dosage for Helicobacter Pylori eradication
  • Dosage for Zollinger-Ellison Syndrome
  • Dosage for acid-related Dyspepsia
  • Dosage for Duodenal and Gastric ulcer
  • Specific dosages for adult and pediatric patients
  • Dosage for risk reduction of rebleeding of Gastric or Duodenal Ulcers

Administration

  • Oral administration with or without a meal
  • Swallowing tablets or capsules whole
  • Oral suspension administration instructions
  • IV Injection solution preparation instructions
  • IV Injection administration instructions and precautions

Interaction

  • Metabolism in the liver by CYP2C19 and CYP3A4
  • No likely inhibition of CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
  • No clinically relevant interactions with specific drugs
  • Potential interference with CYP2C19 and gastric pH-dependent drug absorption
  • Increase in plasma levels with specific drug combination

Contraindications

  • Contraindicated in patients with known hypersensitivity

Side Effects

  • Frequently occurring adverse events
  • Types of related adverse events during maintenance treatment

Pregnancy & Lactation

  • Lack of adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Lack of studies on the excretion of esomeprazole in milk
  • Recommendation to discontinue breastfeeding if use is considered essential

Precautions & Warnings

  • Symptomatic response does not preclude gastric malignancy
  • Instruction for patients who have difficulty swallowing capsules
  • Use of antacids while taking esomeprazole

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in patients with renal impairment

Overdose Effects

  • Lethal dose in rats
  • Signs of acute toxicity
  • No reports of overdose with esomeprazole
  • Lack of specific antidote
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Recommended temperature and environmental conditions for storage

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • No specific structural information provided

Common Questions about Esonix 40 mg Tablet

  • Description of Esonix 40 mg Tablet as a proton pump inhibitor
  • Multiple uses of Esonix 40 mg Tablet
  • Common side effects of Esonix 40 mg Tablet
  • Recommendation regarding use during pregnancy or breastfeeding
  • Duration for Esonix 40 mg Tablet to start working
  • Quick tips for using Esonix 40 mg Tablet

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