Esonix 40 mg (Tablet (Enteric Coated))
Unit Price: ৳ 10.00 (4 x 14: ৳ 560.00)
Strip Price: ৳ 140.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Relieve chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment for Zollinger-Ellison Syndrome
- Treatment for acid-related Dyspepsia
- Treatment for Duodenal and Gastric ulcer
Pharmacology
- Proton pump inhibitor
- Suppresses gastric acid secretion
- Specific inhibition of the H+/K+-ATPase
- Better acid control than racemic proton pump inhibitors
- Enteric-coated pellet formulation of esomeprazole magnesium
- Peak plasma levels occur at approximately 1.5 hours after oral administration
Dosage
- Oral dosage form
- IV Injection or IV infusion
- Dosage for healing of erosive esophagitis
- Dosage for symptomatic GERD
- Dosage for Helicobacter Pylori eradication
- Dosage for Zollinger-Ellison Syndrome
- Dosage for acid-related Dyspepsia
- Dosage for Duodenal and Gastric ulcer
- Specific dosages for adult and pediatric patients
- Dosage for risk reduction of rebleeding of Gastric or Duodenal Ulcers
Administration
- Oral administration with or without a meal
- Swallowing tablets or capsules whole
- Oral suspension administration instructions
- IV Injection solution preparation instructions
- IV Injection administration instructions and precautions
Interaction
- Metabolism in the liver by CYP2C19 and CYP3A4
- No likely inhibition of CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
- No clinically relevant interactions with specific drugs
- Potential interference with CYP2C19 and gastric pH-dependent drug absorption
- Increase in plasma levels with specific drug combination
Contraindications
- Contraindicated in patients with known hypersensitivity
Side Effects
- Frequently occurring adverse events
- Types of related adverse events during maintenance treatment
Pregnancy & Lactation
- Lack of adequate and well-controlled studies in pregnant women
- No teratogenic effects observed in animal studies
- Lack of studies on the excretion of esomeprazole in milk
- Recommendation to discontinue breastfeeding if use is considered essential
Precautions & Warnings
- Symptomatic response does not preclude gastric malignancy
- Instruction for patients who have difficulty swallowing capsules
- Use of antacids while taking esomeprazole
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety and efficacy observed between the elderly and younger individuals
- No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
- Pharmacokinetics not expected to be altered in patients with renal impairment
Overdose Effects
- Lethal dose in rats
- Signs of acute toxicity
- No reports of overdose with esomeprazole
- Lack of specific antidote
- Treatment should be symptomatic and supportive
Storage Conditions
- Recommended temperature and environmental conditions for storage
Chemical Structure
- Molecular Formula: C17H19N3O3S
- No specific structural information provided
Common Questions about Esonix 40 mg Tablet
- Description of Esonix 40 mg Tablet as a proton pump inhibitor
- Multiple uses of Esonix 40 mg Tablet
- Common side effects of Esonix 40 mg Tablet
- Recommendation regarding use during pregnancy or breastfeeding
- Duration for Esonix 40 mg Tablet to start working
- Quick tips for using Esonix 40 mg Tablet