Amifex 60 mg (Tablet)

Unit Price: ৳ 3.50

Medicine Details

Title

  • Amifex 60 mg Tablet

Categories

  • Antihistamine
  • Allergic Rhinitis Relief
  • Chronic Idiopathic Urticaria Relief
  • Non-sedating Antihistamines

Description

  • Relieves symptoms associated with seasonal and perennial allergic rhinitis
  • Relieves symptoms associated with chronic idiopathic urticaria
  • Improves health-related quality of life and work/activity productivity
  • Blocks histamine production during allergic reactions
  • Reduces symptoms such as sneezing, rhinorrhea, lacrimation, itchy, red eyes, itchy nose/palate/throat, pruritus, and wheals
  • Does not cross the blood-brain barrier, unlikely to cause significant CNS effects

Dosage & Administration

  • Allergic Rhinitis:
    • Adults and Children 12 years and older:
      • 60 mg twice daily
      • 120 mg once daily
      • 180 mg once daily
  • Chronic Idiopathic Urticaria:
    • Adults and Children 12 years and older:
      • 60 mg twice daily
      • 120 mg once daily
      • 180 mg once daily

Interaction

  • Does not undergo hepatic biotransformation
  • Coadministration with erythromycin or ketoconazole can increase fexofenadine levels in plasma
  • No interaction with omeprazole observed
  • Antacids containing aluminium and magnesium hydroxide can reduce bioavailability

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side Effects

  • Adults:
    • Headache
    • Drowsiness
    • Dizziness
    • Nausea
    • Fatigue
    • Hypersensitivity reactions with manifestations such as angioedema, chest tightness, dyspnoea, flushing, systemic anaphylaxis
    • Insomnia
    • Nervousness
    • Tachycardia
    • Palpitations
    • Diarrhea
    • Rash
    • Urticaria
    • Pruritus

Pregnancy & Lactation

  • Pregnancy:
    • No adequate data available for use in pregnant women
    • Not recommended unless clearly necessary
  • Lactation:
    • Not recommended for breastfeeding mothers

Precautions & Warnings

  • Administer with care in older people and renally or hepatically impaired patients
  • Patients with a history of or ongoing cardiovascular disease should be warned
  • Unlikely to produce an effect on the ability to drive or use machines
  • Caution advised for sensitive individuals

Use in Special Populations

  • Renal and Hepatic Impaired Patient:
    • Altered pharmacokinetics in individuals with renal impairment
    • Moderate to severe hepatic disease does not substantially affect the pharmacokinetics
  • Elderly Patient:
    • Adverse events were similar to those under 65 years of age
    • Altered pharmacokinetics in individuals over 65 years of age

Overdose Effects

  • Dizziness
  • Drowsiness
  • Fatigue
  • Dry mouth
  • Maximum tolerated dose not established
  • Symptomatic and supportive treatment recommended

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C32H39NO4

Common Questions about Amifex 60 mg Tablet

  • Amifex 60 mg Tablet is an antihistamine used for allergic rhinitis and urticaria relief
  • Reported side effects include Vomiting, Headache, Coughing, Diarrhea, Painful menstruation, Hives, Redness of skin, and Swelling of face, lips, eyelids, tongue, hands, and feet
  • Instructions for storage and disposal include keeping in a cool dry place in its original pack, and away from children and pets
  • Can cause sleepiness and should not be overdosed
  • Starts working within 1 hour and peak benefit observed within 6 hours
  • Can relieve symptoms of outdoor and indoor allergies
  • Counseling is given on coping with dizziness, avoiding antacids, and taking as per doctor's recommendation
  • Consumption of certain fruit juices should be avoided
  • Caution advised for those with heart problems
  • Quick tips include blocking histamine effects, minimal sleepiness, avoiding specific fruit juices, managing nausea, and avoiding antacids

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