Odofex 120 mg (Tablet)

Unit Price: ৳ 8.00 (50's pack: ৳ 400.00)

Medicine Details

Category Details
Generic Fexofenadine hydrochloride
Company Cosmic pharma ltd

Indications

  • Relief of symptoms of seasonal allergic rhinitis
  • Relief of symptoms of perennial allergic rhinitis
  • Improves health-related quality of life
  • Relief of symptoms of chronic idiopathic urticaria
  • Reduces signs and symptoms of chronic idiopathic urticaria
  • Improves work/activity productivity

Pharmacology

  • H1 histamine receptor-mediated hypersensitivity
  • Degranulation of mast cells and basophils
  • Release of histamine and inflammatory mediators
  • Potent and selective affinity for H1 receptors
  • No antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
  • Does not cross the blood-brain barrier

Dosage and administration

  • Dosage for adults and children 12 years and older
  • Dosage for children 6 to 11 years
  • Dosage for children 2 to 11 years
  • Recommended dosage for allergic rhinitis
  • Recommended dosage for chronic idiopathic urticaria
  • Adjusted dosage in case of impaired renal function

Interaction

  • No hepatic biotransformation
  • No interaction with other medicinal products through hepatic mechanisms
  • Increased plasma level with erythromycin or ketoconazole coadministration
  • No interaction between fexofenadine and omeprazole
  • Reduction in bioavailability with antacid coadministration

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride

Side effects

  • Nervous system disorders: headache, drowsiness, dizziness
  • Gastrointestinal disorders: nausea
  • Immune system disorders: hypersensitivity reactions
  • Psychiatric disorders: insomnia, nervousness
  • Cardiac disorders: tachycardia, palpitations
  • Skin and subcutaneous tissue disorders: rash, urticaria, pruritus

Pregnancy and lactation

  • Limited data in pregnant women
  • No data on the content of human milk after administration
  • Not recommended for mothers breastfeeding their babies
  • No human data on the effect on fertility
  • No significant effect on fertility in mice

Precautions and warnings

  • Limited data in older people and renally or hepatically impaired patients
  • Careful administration in special groups
  • Warning for patients with history of or ongoing cardiovascular disease
  • Unlikely to produce significant effects on the ability to drive or use machines

Use in special populations

  • Altered pharmacokinetics in individuals with renal impairment
  • Dose adjustment for patients with decreased renal function
  • Moderate to severe hepatic disease does not substantially affect the pharmacokinetics
  • Similar adverse events in elderly patients compared to patients under 65 years of age
  • Altered pharmacokinetics in individuals over 65 years of age

Overdose effects

  • Dizziness, drowsiness, fatigue, dry mouth
  • No development of clinically significant adverse reactions at high doses
  • Standard measures for removal of unabsorbed medicinal product
  • Symptomatic and supportive treatment recommended
  • Haemodialysis does not effectively remove Odofex from blood

Therapeutic class

  • Non-sedating antihistamines

Storage conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical structure

  • Molecular Formula: C32H39NO4

Common questions

  • What is Odofex 120 mg Tablet?
  • What are the uses of Odofex 120 mg Tablet?
  • What are the Side Effects of Odofex 120 mg Tablet?
  • What are the instructions for storage and disposal Odofex 120 mg Tablet?
  • Can Odofex 120 mg Tablet make you sleepy?
  • Can you overdose on Odofex 120 mg Tablet?
  • How quickly does Odofex 120 mg Tablet work?
  • Does Odofex 120 mg Tablet relieve symptoms of outdoor and indoor allergies?
  • How to cope with dizziness caused by Odofex 120 mg Tablet?
  • Can I take antacids while taking Odofex 120 mg Tablet?
  • How should I take Odofex 120 mg Tablet?
  • Is there any food or drink that I need to avoid while taking Odofex 120 mg Tablet?
  • Can Odofex 120 mg Tablet cause heart problems?
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