Rafex 120 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Title

  • Rafex 120 mg Tablet

Category

  • Non-sedating antihistamines

Indications

  • Relief of symptoms associated with seasonal and perennial allergic rhinitis in adults and children 12 years of age and over
  • Relief of symptoms associated with chronic idiopathic urticaria in adults and children 12 years of age and older
  • Improves health-related quality of life and work/activity productivity for allergic rhinitis
  • Significantly reduces the signs and symptoms of chronic idiopathic urticaria

Pharmacology

  • Fexofenadine is an 'inverse agonist' of the H1 receptor
  • Selective affinity for H1 receptors
  • No evidence of antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
  • Does not cross the blood-brain barrier

Dosage & Administration

  • Adults and children 12 years and older: 60 mg twice daily or 120 mg once daily or 180 mg once daily
  • Children from 2 to 11 years: Suspension - 30 mg or 5 ml twice daily
  • Instructions for dosage adjustment in case of impaired renal function

Interaction

  • No hepatic biotransformation
  • Coadministration with erythromycin or ketoconazole leads to increased level of fexofenadine in plasma
  • No interaction between fexofenadine and omeprazole
  • Reduction in bioavailability when coadministered with antacids containing aluminium and magnesium hydroxide

Contraindications

  • Known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side Effects

  • Headache, drowsiness, dizziness, nausea, and fatigue reported in clinical trials
  • Post-marketing surveillance reports hypersensitivity reactions, tachycardia, palpitations, diarrhea, and skin disorders

Pregnancy & Lactation

  • Limited data on use during pregnancy
  • Not recommended for nursing mothers

Precautions & Warnings

  • Limited data for older people and renally or hepatically impaired patients
  • Warning for patients with a history of or ongoing cardiovascular disease
  • Unlikely to produce an effect on the ability to drive or use machines

Use in Special Populations

  • Instructions for dosage adjustment in renal impaired patients
  • Altered pharmacokinetics in individuals with renal impairment and over 65 years of age

Overdose Effects

  • Reported effects include dizziness, drowsiness, fatigue, and dry mouth
  • Maximum tolerated dose not established
  • Recommendation for symptomatic and supportive treatment

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C32H39NO4
  • Chemical Structure Image

Common Questions

  • What is Rafex 120 mg Tablet?
  • What are the uses of Rafex 120 mg Tablet?
  • What are the Side Effects of Rafex 120 mg Tablet?
  • What are the instructions for storage and disposal of Rafex 120 mg Tablet?
  • Can Rafex 120 mg Tablet make you sleepy?
  • Can you overdose on Rafex 120 mg Tablet?
  • How quickly does Rafex 120 mg Tablet work?
  • Does Rafex 120 mg Tablet relieve symptoms of outdoor and indoor allergies?
  • How to cope with dizziness caused by Rafex 120 mg Tablet?
  • Can I take antacids while taking Rafex 120 mg Tablet?
  • How should I take Rafex 120 mg Tablet?
  • Is there any food or drink that I need to avoid while taking Rafex 120 mg Tablet?
  • Can Rafex 120 mg Tablet cause heart problems?
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