Fexirin 120 mg (Tablet)

Unit Price: ৳ 6.00 (50's pack: ৳ 300.00)

Medicine Details

Indications

  • Relief of symptoms associated with allergic rhinitis
  • Relief of symptoms associated with chronic idiopathic urticaria
  • Improves health-related quality of life and work/activity productivity

Pharmacology

  • Fexofenadine is an 'inverse agonist' of the H1 receptor
  • Selective affinity for H1 receptors
  • No evidence of carrying antidopaminergic, antiserotonergic, anticholinergic, sedative, or adrenergic blocking activity
  • Does not cross the blood-brain barrier

Dosage & Administration

  • Different dosage for adults and children
  • Varied dosage based on age and impaired renal function
  • Tablet and suspension options for different age groups

Interaction

  • No hepatic biotransformation
  • Increased level of fexofenadine in plasma when coadministered with erythromycin or ketoconazole
  • No interaction between fexofenadine and omeprazole
  • Reduction in bioavailability when administered with antacids containing aluminium and magnesium hydroxide

Contraindications

  • Contraindicated in patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients

Side Effects

  • Reported undesirable effects in clinical trials and post-marketing surveillance
  • Commonly reported effects include headache, drowsiness, nausea, and fatigue

Pregnancy & Lactation

  • Limited data in pregnant women
  • Fexofenadine found to cross into human breast milk
  • Not recommended for mothers breast-feeding their babies
  • No human data on the effect of Fexofenadine hydrochloride on fertility

Precautions & Warnings

  • Limited data in older people and renally or hepatically impaired patients
  • Adverse reactions associated with cardiovascular disease
  • Unlikely to produce an effect on the ability to drive or use machines
  • Altered pharmacokinetics in renal impairment and individuals over 65 years of age

Use in Special Populations

  • Altered pharmacokinetics in individuals with renal impairment
  • Moderate to severe hepatic disease does not substantially affect the pharmacokinetics of fexofenadine
  • Similar adverse events in elderly patients compared to patients under 65 years of age

Overdose Effects

  • Reported effects of dizziness, drowsiness, fatigue, and dry mouth with overdose
  • Single doses up to 800 mg administered to healthy subjects
  • Standard measures and symptomatic treatment recommended

Therapeutic Class

  • Non-sedating antihistamines

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C32H39NO4
  • Chemical Structure Image Available

Common Questions about Fexirin 120 mg Tablet

  • Information about the medication's working mechanism
  • Uses of the tablet for allergic rhinitis and urticaria
  • Reported side effects
  • Instructions for storage and disposal
  • Potential to cause sleepiness
  • Onset and peak benefit duration
  • Ability to relieve symptoms of outdoor and indoor allergies
  • Coping with dizziness
  • Interaction with antacids
  • Guidance on intake
  • Foods or drinks to avoid while taking the tablet
  • Potential to cause heart problems
  • Quick tips for usage

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