Migon 5 mg (Tablet)
Unit Price: ৳ 3.00 (4 x 14: ৳ 168.00)
Strip Price: ৳ 42.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Flunarizine |
| Company | Drug international ltd |
| Also available as |
Indications
- Prophylaxis of classic (with aura) or common (without aura) migraine
- Symptomatic treatment of vestibular vertigo
- Peripheral Vascular Disease (PVD)
- Motion sickness
- Refractory epilepsy resistant to conventional antiepileptic therapy
Pharmacology
- Selective calcium channel antagonist
- Reduces excessive transmembrane influx of calcium
- Antihistaminic properties
- Sedative properties
- Binds at an affinity of 99% to plasma protein
Dosage & Administration
- Starting Dose: 10 mg at night in patients less than 65 years of age
- Starting Dose: 5 mg daily in patients older than 65 years
- Maintenance Treatment: Decreased dose with medicine-free days
- Peripheral Vascular Disease dosage: 10 mg twice daily, up to 30 mg per day
- Vertigo & motion sickness dosage: 10-20 mg daily for adults, 5 mg daily for children
- Epileptic seizure dosage: 15-20 mg daily in adults, 5 to 10 mg daily for children as add-on therapy
Interaction
- Galactorrhoea reported in few women on oral contraceptives
- Hepatic enzyme inducers may interact with Migon
- Hepatic enzyme inducers include Carbamazepine and Phenytoin
Contraindications
- Hypersensitivity to Flunarizine
- Contra-indicated in patients with a history of depressive illness
- Contra-indicated in patients with pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders
Side Effects
- Drowsiness and/or fatigue
- Weight gain and/or increased appetite
- Depression
- Extrapyramidal symptoms (bradykinesia, rigidity, akathisia, orofacial dyskinesia, tremor)
- Heartburn
- Nausea
- Gastralgia
- Insomnia
- Anxiety
- Galactorrhoea
- Dry mouth
- Muscle ache
- Skin rash
Pregnancy & Lactation
- Safety in pregnancy and lactation has not been established
Precautions & Warnings
- May lead to drowsiness
- Aggravated by simultaneous intake of alcohol or other central nervous system depressants
- Not suited for aborting a migraine attack
- May give rise to extrapyramidal and depressive symptoms
- Reveals Parkinsonism, especially in predisposed patients such as the elderly
- Cautioned against driving motor vehicles or performing other potentially hazardous tasks
- Not suited for aborting a migraine attack
Therapeutic Class
- Miscellaneous prophylactic migraine preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children