Migon 10 mg (Tablet)

Unit Price: ৳ 5.00 (4 x 14: ৳ 280.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Flunarizine
Company Drug international ltd
Also available as

Title

  • Migon

Categories

  • Medicine
  • Pharmaceutical

Description

  • Migon is indicated for migraine prophylaxis, vestibular vertigo, peripheral vascular disease, motion sickness, and refractory epilepsy resistant to conventional antiepileptic therapy. It is a selective calcium channel antagonist with some antihistaminic and sedative properties.

Indication

  • Prophylaxis of classic (with aura) or common (without aura) migraine
  • Symptomatic treatment of vestibular vertigo
  • Peripheral Vascular Disease (PVD)
  • Motion sickness
  • Refractory epilepsy resistant to conventional antiepileptic therapy

Pharmacology

  • Selective calcium channel antagonist
  • Prevents cellular calcium overload
  • Has some antihistaminic and sedative properties
  • Binds at an affinity of 99% to plasma protein.

Dosage and administration

  • Starting Dose: 10 mg at night in patients less than 65 years of age and 5 mg daily in patients older than 65 years
  • Maintenance Treatment: Decrease to 5 days treatment at the same daily dose with two successive medicine free days every week
  • Peripheral Vascular Disease: 10 mg twice daily, up to 30 mg per day if required
  • Vertigo & motion sickness: 10-20 mg daily for adults and 5 mg daily for children (> 40 kg)
  • Epileptic seizure: 15-20 mg daily in adults and 5 to 10 mg daily for children as an add-on therapy

Interaction

  • Galactorrhoea reported in some women on oral contraceptives within the first two months of Migon treatment
  • Hepatic enzyme inducers such as Carbamazepine and Phenytoin may interact with Migon by increasing its metabolism

Contraindications

  • Hypersensitivity to Flunarizine
  • Contra-indicated in patients with a history of depressive illness, pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders

Side effects

  • Drowsiness and/or fatigue
  • Weight gain and/or increased appetite
  • Adverse experiences during chronic treatment with Migon: depression, extrapyramidal symptoms, heartburn, nausea, gastralgia, insomnia, anxiety, galactorrhoea, dry mouth, muscle ache, skin rash

Pregnancy and lactation

  • Safety in pregnancy and lactation has not been established

Precautions and warnings

  • May lead to drowsiness, aggravated by simultaneous intake of alcohol or other central nervous system depressants
  • Not suited for aborting a migraine attack
  • May give rise to extrapyramidal and depressive symptoms and reveal Parkinsonism, especially in predisposed patients such as the elderly

Therapeutic class

  • Miscellaneous prophylactic migraine preparations

Storage conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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