Esoprol 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (6 x 10: ৳ 300.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Ziska pharmaceuticals ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Management of acid-related Dyspepsia
- Healing of Duodenal & Gastric ulcers
Pharmacology
- Proton pump inhibitor
- Suppresses gastric acid secretion
- Specific inhibition of the H+/K+-ATPase
- Enteric-coated pellet formulation
- Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
- 97% bound to plasma proteins
- Systemic bioavailability is approximately 90%
- Peak plasma levels occur at approximately 1.5 hours
Dosage
- Oral dosage form available
- Dosage varies based on indication
- IV Injection and IV infusion options available
- Different dosages for adult and pediatric patients
Administration
- Tablet or capsule should be swallowed whole
- Oral suspension should be mixed with water
- IV injection prepared by adding 0.9% Sodium Chloride
- Specific instructions for administering through a nasogastric or gastric tube
Interaction
- Extensively metabolized in the liver by CYP2C19 and CYP3A4
- No clinically relevant interactions with certain drugs
- Potential interference with drug absorption where gastric pH is important
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects observed in animal studies
- Excretion in milk not studied
- Breast-feeding should be discontinued if essential
Precautions & Warnings
- Symptomatic response does not rule out gastric malignancy
- Specific instructions for patients with difficulty swallowing capsules
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety and efficacy observed between the elderly and younger individuals
- No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
- Pharmacokinetics not expected to be altered in patients with renal impairment
Overdose Effects
- Lethal effects observed in animal studies at high doses
- No specific antidote known
- Treatment should be symptomatic and supportive
Storage Conditions
- Store at a temperature not exceeding 30°C
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure available
Common Questions about Esoprol 20 mg Capsule
- Proton pump inhibitor
- Multiple uses including treatment of GERD, ulcers, and conditions involving excessive stomach acid
- Common side effects include headaches, diarrhea, nausea, and constipation
- Considerations for pregnant or breastfeeding individuals
- Quick tips for usage and potential side effects
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