Lunarzin 10 mg (Tablet)

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Flunarizine
Company Ibn sina pharmaceuticals ltd
Also available as

Indications

  • Prophylaxis of classic (with aura) or common (without aura) migraine
  • Symptomatic treatment of vestibular vertigo (due to a diagnosed functional disorder of the vestibular system)
  • Peripheral Vascular Disease (PVD)
  • Motion sickness
  • Refractory epilepsy resistant to conventional antiepileptic therapy

Pharmacology

  • Selective calcium channel antagonist
  • Reduces excessive transmembrane influx of calcium
  • Antihistaminic properties
  • Sedative properties
  • Binds at an affinity of 99% to plasma protein

Dosage & Administration

  • Migraine Prophylaxis
  • Starting Dose: 10 mg at night in patients less than 65 years of age and 5 mg daily in patients older than 65 years
  • Maintenance Treatment: Dose should be decreased to 5 days treatment at the same daily dose with two successive medicine free days every week
  • Peripheral Vascular Disease: 10 mg twice daily, up to 30 mg per day if required
  • Vertigo & motion sickness: 10-20 mg daily for adults, 5 mg daily for children (>40 kg)
  • Epileptic seizure: 15-20 mg daily in adults, 5 to 10 mg daily for children as an add-on therapy

Interaction

  • Galactorrhoea reported in women on oral contraceptives within the first two months of Lunarzin treatment
  • Hepatic enzyme inducers such as Carbamazepine and Phenytoin may interact with Lunarzin by increasing its metabolism

Contraindications

  • Hypersensitivity to Flunarizine
  • Contra-indicated in patients with a history of depressive illness
  • Pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders

Side Effects

  • Drowsiness and/or fatigue
  • Weight gain and/or increased appetite
  • Depression, particularly in female patients with a history of depressive illness
  • Extrapyramidal symptoms, particularly in elderly patients
  • Heartburn
  • Nausea
  • Gastralgia
  • Insomnia
  • Anxiety
  • Galactorrhoea
  • Dry mouth
  • Muscle ache
  • Skin rash

Pregnancy & Lactation

  • Safety in pregnancy and lactation has not been established

Precautions & Warnings

  • May lead to drowsiness, aggravated by simultaneous intake of alcohol or CNS depressants
  • Caution against driving or performing potentially hazardous tasks
  • Not suited for aborting a migraine attack
  • May reveal Parkinsonism, especially in predisposed patients such as the elderly

Therapeutic Class

  • Miscellaneous prophylactic migraine preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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