Lunarzin 10 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Flunarizine |
Company | Ibn sina pharmaceuticals ltd |
Also available as |
Indications
- Prophylaxis of classic (with aura) or common (without aura) migraine
- Symptomatic treatment of vestibular vertigo (due to a diagnosed functional disorder of the vestibular system)
- Peripheral Vascular Disease (PVD)
- Motion sickness
- Refractory epilepsy resistant to conventional antiepileptic therapy
Pharmacology
- Selective calcium channel antagonist
- Reduces excessive transmembrane influx of calcium
- Antihistaminic properties
- Sedative properties
- Binds at an affinity of 99% to plasma protein
Dosage & Administration
- Migraine Prophylaxis
- Starting Dose: 10 mg at night in patients less than 65 years of age and 5 mg daily in patients older than 65 years
- Maintenance Treatment: Dose should be decreased to 5 days treatment at the same daily dose with two successive medicine free days every week
- Peripheral Vascular Disease: 10 mg twice daily, up to 30 mg per day if required
- Vertigo & motion sickness: 10-20 mg daily for adults, 5 mg daily for children (>40 kg)
- Epileptic seizure: 15-20 mg daily in adults, 5 to 10 mg daily for children as an add-on therapy
Interaction
- Galactorrhoea reported in women on oral contraceptives within the first two months of Lunarzin treatment
- Hepatic enzyme inducers such as Carbamazepine and Phenytoin may interact with Lunarzin by increasing its metabolism
Contraindications
- Hypersensitivity to Flunarizine
- Contra-indicated in patients with a history of depressive illness
- Pre-existing symptoms of Parkinson's disease or other extrapyramidal disorders
Side Effects
- Drowsiness and/or fatigue
- Weight gain and/or increased appetite
- Depression, particularly in female patients with a history of depressive illness
- Extrapyramidal symptoms, particularly in elderly patients
- Heartburn
- Nausea
- Gastralgia
- Insomnia
- Anxiety
- Galactorrhoea
- Dry mouth
- Muscle ache
- Skin rash
Pregnancy & Lactation
- Safety in pregnancy and lactation has not been established
Precautions & Warnings
- May lead to drowsiness, aggravated by simultaneous intake of alcohol or CNS depressants
- Caution against driving or performing potentially hazardous tasks
- Not suited for aborting a migraine attack
- May reveal Parkinsonism, especially in predisposed patients such as the elderly
Therapeutic Class
- Miscellaneous prophylactic migraine preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children