Esoprol 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 8.00 (4 x 8: ৳ 256.00)
Strip Price: ৳ 64.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Ziska pharmaceuticals ltd |
Also available as |
Title
Esoprol 40 mg Capsule
Categories
- Medicine
- Health
- Pharmacology
Description
Esoprol 40 mg Capsule is a proton pump inhibitor (PPI) indicated for relieving chronic heartburn symptoms, healing erosive esophagitis, maintenance of healing, eradication of Helicobacter pylori infection, treating Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers.
Attributes
- Indications:
- Relieves chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment for Zollinger-Ellison Syndrome
- Manages acid-related dyspepsia
- Treats duodenal and gastric ulcers
- Pharmacology:
- Proton pump inhibitor
- Suppresses gastric acid secretion
- Specific inhibition of the H+/K+-ATPase
- Provides better acid control than racemic proton pump inhibitors
- Absorption occurs approximately 1.5 hours after oral administration
- Distribution: 97% bound to plasma proteins
- Extensively metabolized in the liver by the cytochrome P450 (CYP) enzyme system
- Excretion: Less than 1% excreted in urine
- Dosage:
- Oral dosage form for various conditions such as healing of erosive esophagitis, symptomatic GERD, Helicobacter pylori eradication, Zollinger-Ellison Syndrome, acid-related dyspepsia, duodenal and gastric ulcers
- IV Injection or IV infusion for GERD with Erosive Esophagitis in adult and pediatric patients, and risk reduction of rebleeding of Gastric or Duodenal Ulcers in adult patients
- Specific dosages for body weights and age groups
- Administration:
- Tablet or capsule: Should be swallowed whole and taken one hour before a meal
- Oral Suspension: Specific instructions for preparation and administration
- IV Injection: Preparation of solution and administration guidelines
- Interaction:
- Metabolized in the liver by CYP2C19 and CYP3A4
- Not likely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1, and 3A4
- Potential interactions with CYP2C19 and drugs impacted by gastric pH
- Contraindications:
- Contraindicated in patients with known hypersensitivity to any of the formulation
- Side Effects:
- Frequently occurring adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, and dry mouth
- Pregnancy & Lactation:
- No adequate and well-controlled studies in pregnant women
- Animal studies showed no teratogenic effects
- Excretion in milk not studied
- Breastfeeding to be discontinued if essential
- Precautions & Warnings:
- Symptomatic response does not preclude the presence of gastric malignancy
- Specific instructions for patients with difficulty swallowing capsules
- Use in Special Populations:
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety and efficacy observed between elderly and younger individuals
- No dosage adjustment recommended for mild to moderate hepatic insufficiency
- Pharmacokinetics not expected to be altered in patients with renal impairment
- Overdose Effects:
- Lethal effects observed in animal studies
- No specific antidote known
- Treatment to be symptomatic and supportive
- Storage Conditions:
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture
- Keep out of reach of children
- Chemical Structure:
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image Provided
- Common Questions about Esoprol 40 mg Capsule:
- Information on usage, side effects, pregnancy & breastfeeding, onset of action, and quick tips
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