Danxit 0.5 mg+10 mg (Tablet)
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Flupentixol melitracen |
Company | Astra biopharmaceuticals ltd |
Title
- Flupentixol and Melitracen Tablet
Categories
- Anxiolytics & Anti-depressants
Description
- This tablet is indicated for Anxiety, Depression, Apathy, Psychogenic depression, Depressive neurosses, Masked depression, Menopausal depression, Dysphoria and depression in alcoholics and drug addicts.
- Flupentixol has neuroleptic, anxiolytic, and antidepressant properties in small doses, while Melitracen has bipolar thymoleptic properties in low doses.
- Adult dosage is usually 2 tablets orally daily in the morning and noon, and 1 tablet for elderly patients in the morning, with a maintenance dose of 1 tablet orally in the morning. Extra treatment with a sedative in the acute phase is recommended for insomnia or severe restlessness.
- It may enhance the response to alcohol, barbiturates, and other CNS depressants. Simultaneous administration of MAO-inhibitors may cause hypertensive crises.
- Contraindicated in immediate recovery phase after myocardial infarction, defects in bundle-branch conduction, untreated narrow-angle glaucoma, acute alcohol, barbiturate and opiate intoxications, and to patients who have received an MAO-inhibitor within two weeks. Not recommended for excitable or overactive patients.
- Rare side effects in recommended doses include transient restlessness and insomnia. Preferably not to be given during pregnancy and lactation. If previously treated with tranquillizers with a sedative effect, they should be withdrawn gradually.
- In cases of overdosage, symptoms of intoxications by melitracen dominate, especially of anticholinergic nature. Symptomatic and supportive treatment should be instituted.
Dimensions
Color Options
Functions
- Anxiety treatment
- Depression treatment
- Apathy treatment
- Activating properties
- Neuroleptic properties
- Anxiolytic properties
- Antidepressant properties
Materials
Technical Specifications
- Maximal serum concentration is reached in about 4 hours after oral administration of flupentixol and melitracen.
- Biological half-life of flupentixol is about 35 hours and that of melitracen is about 19 hours.
- The combination of flupentixol and melitracen does not seem to influence the pharmacokinetic properties of the individual compounds.
Design Elements
Usability Features
Indications
- Anxiety
- Depression
- Apathy
- Psychogenic depression
- Depressive neurosses
- Masked depression
- Psychosomatic affections accompanied by anxiety and apathy
- Menopausal depressions
- Dysphoria
- Depression in alcoholics and drug addicts
Mode of Action
- Flupentixol - neuroleptic with anxiolytic and antidepressant properties in small doses
- Melitracen - bipolar thymoleptic with activating properties in low doses
Dosage & Administration
- Adults: 2 tablets orally daily in the morning and noon, with morning dose potentially increased to 2 tablets in severe cases.
- Elderly patients: 1 tablet in the morning.
- Maintenance dose: 1 tablet orally in the morning, with additional treatment with a sedative in acute phase for insomnia or severe restlessness.
Interaction
- May enhance the response to alcohol, barbiturates, and other CNS depressants.
- Simultaneous administration of MAO-inhibitors may cause hypertensive crises.
- Neuroleptics and thymoleptics reduce the antihypertensive effect of guanethidine and similar acting compounds, and thymoleptics enhance the effects of adrenaline and noradrenaline.
Contraindications
- Immediate recovery phase after myocardial infarction
- Defects in bundle-branch conduction
- Untreated narrow-angle glaucoma
- Acute alcohol, barbiturate and opiate intoxications
- Patients who have received an MAO-inhibitor within two weeks
- Not recommended for excitable or overactive patients
Side Effects
- In recommended doses, rare side effects include transient restlessness and insomnia.
Pregnancy & Lactation
- Preferably not to be given during pregnancy and lactation.
Precautions & Warnings
- Withdrawal of previous tranquillizers with sedative effect should be gradual.
Overdose Effects
- In cases of overdosage, symptoms of intoxications by melitracen dominate, especially of anticholinergic nature. Symptomatic and supportive treatment should be instituted.
Therapeutic Class
- Combined anxiolytics & anti-depressant drugs
Storage Conditions
- Store at a temperature not exceeding 30°C in a dry place. Protect from light. Keep out of reach of children.
Common Questions about Danxit 0.5 mg Tablet
- Danxit 0.5 mg Tablet consists of Flupentixol & Melitracen, and is used to treat Anxiety, Depression, Apathy, Psychogenic depression, Depressive neurosses, Masked depression, and Menopausal depression.