Fluticare 0.05% (Cream)

10 gm tube: ৳ 96.00

Medicine Details

Category	Details
Generic	Fluticasone propionate topical
Company	Ibn sina pharmaceuticals ltd
Also available as	Fluticare 0005 ointment

Glucocorticoid with high topical anti-inflammatory potency
Low HPA-axis suppressive activity after dermal administration
Therapeutic index greater than most commonly available steroids
High degree of selectivity for glucocorticoid receptor
In vitro studies show strong affinity and agonist activity at human glucocorticoid receptors
Weak affinity for progesterone receptor
Virtually no affinity for mineralocorticoid, estrogen, or androgen receptors
Therapeutic potency related to the half-life of the glucocorticoid-receptor complex (approximately 10 hours)

Rosacea
Acne vulgaris
Perioral dermatitis
Primary cutaneous viral infections (e.g., Herpes simplex, chicken pox)
Hypersensitivity to any of the ingredients
Perianal and genital pruritus
Not indicated in treatment of primarily infected skin lesions caused by fungi or bacteria
Not indicated in children under one year of age

Local burning
Pruritus
Signs of hypersensitivity
Local atrophic changes in the skin (thinning, striae, dilatation of superficial blood vessels, hypertrichosis, hypopigmentation)
Secondary infection
Allergic contact dermatitis
Exacerbation of the signs and symptoms of the dermatoses
Features of hypercorticism with prolonged use of large amounts
More likely to occur in infants and children, especially with occlusive dressings

Consideration of use during pregnancy based on expected benefit vs. possible risk to the fetus
Excretion into human breast milk not investigated
Low plasma levels in patients following dermal application
Therapeutic benefits vs. potential hazards in breastfeeding mothers and babies

Very low propensity for systemic absorption
Prolonged application of high doses to large areas might lead to adrenal suppression
Children may absorb proportionally larger amounts
Atropic changes on the face after prolonged treatment
Appropriate antimicrobial therapy for treating infected inflammatory lesions
Withdrawal and systemic administration of antimicrobial agents for spread of infection
Encouragement of bacterial infection with occlusive dressing