Seraflo (25 mcg+250 mcg)/puff (Inhaler)

60 metered doses: ৳ 430.00

Medicine Details

Category Details
Generic Salmeterol fluticasone propionate
Company Drug international ltd
Also available as
Seraflo 25 mcg inhaler Seraflo 50 mcg inhalation capsule Seraflo 50 mcg inhalation capsule

Indications

  • Regular treatment of asthma
  • Combination product (long-acting β2-agonist and inhaled corticosteroid) use
  • Control of asthma not adequately managed with inhaled corticosteroids
  • Control of asthma not managed with inhaled short acting β2-agonist
  • Usual control on both inhaled corticosteroid and long-acting β2-agonist

Pharmacology

  • Salmeterol Xinafoate - selective, long-acting beta-2 agonist
  • Fluticasone Propionate - corticosteroid with glucocorticoid activity
  • Topical effect on the lungs without systemic effects at usual dose
  • Salmeterol protects against symptoms, Fluticasone Propionate improves lung function
  • Convenient regime for patients on concurrent β-agonist and inhaled corticosteroid therapy

Dosage

  • Adult and adolescent dosage
  • Children dosage (4-12 years)
  • Recommended starting dosages
  • Maximum recommended dosage
  • Use for asthma and COPD
  • Maxhaler dosages for asthma
  • Maxhaler dosages for COPD

Administration

  • Steps for effective use of inhaler
  • Instructions for cleaning inhaler

Interaction

  • Avoid non-selective and selective β-blockers in patients with asthma
  • Careful co-administration with strong CYP3A4 inhibitors

Contraindications

  • Hypersensitivity to salmeterol xinafoate or fluticasone propionate
  • Contraindicated in primary treatment of status asthmaticus
  • Contraindicated in acute episodes of asthma with intensive measures

Side Effects

  • Adverse reactions associated with Salmeterol and Fluticasone Propionate
  • Pharmacological side effects of beta-2-agonist treatment
  • Hoarseness, candidiasis, cutaneous hypersensitivity reactions

Pregnancy & Lactation

  • Consideration of use during pregnancy
  • Consideration of use in breast-feeding mothers
  • Insufficient experience of use in human pregnancy and lactation

Precautions & Warnings

  • Avoid initiation in patients during exacerbation of asthma
  • Not for relief of acute symptoms
  • Monitoring for serious asthma-related adverse events
  • Treatment of paradoxical bronchospasm
  • Increased reporting of pneumonia in COPD patients
  • Systemic effects of inhaled corticosteroid

Use in Special Populations

  • Potential reduction in growth velocity in pediatric patients

Overdose Effects

  • Signs and symptoms of Salmeterol overdose
  • Signs and symptoms of Fluticasone Propionate overdose
  • Monitoring of adrenal reserve in cases of overdose

Therapeutic Class

  • Long-acting selective β-adrenoceptor stimulants
  • Respiratory corticosteroids

Storage Conditions

  • Pressurised canister
  • Avoid puncture, breaking or incineration
  • Storage below 30°C
  • Avoid sunlight, heat, and contact with eyes
  • Keep away from children

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