Flumetol (25 mcg+250 mcg)/puff (Inhaler)

Indications

• Regular treatment of asthma
• Combination product for inadequately controlled asthma
• Combination product for adequately controlled asthma

Pharmacology

• Selective, long-acting beta-2 agonist
• Corticosteroid with mainly glucocorticoid activity
• Protects against symptoms
• Improves lung function
• Prevents exacerbations

Dosage

• Adult dosage for inhaler
• Adolescent dosage for inhaler
• Children dosage for inhaler
• Adult and Adolescent dosage for inhalation capsule (asthma)
• Pediatric Patients dosage for inhalation capsule (asthma)
• Inhalation capsule dosage for COPD
• Maxhaler dosage (asthma) for Adults and Adolescents
• Maxhaler dosage (asthma) for Children
• Maxhaler dosage (COPD)
• Special patient groups dosage instructions

Administration

• Instructions for using the inhaler
• Importance of correct and regular use of the inhaler
• Steps for using inhaler effectively
• Instructions for Cleaning Inhaler

Interaction

• Avoidance of non-selective and selective β-blockers
• Potential interactions with strong CYP3A4 inhibitors

Contraindications

• Hypersensitivity to salmeterol xinafoate
• Hypersensitivity to fluticasone propionate
• History of hypersensitivity to any of the excipients
• Primary treatment of status asthmaticus

Side Effects

• Adverse reactions associated with Salmeterol
• Adverse reactions associated with Fluticasone Propionate

Pregnancy & Lactation

• Considerations for administration during pregnancy
• Considerations for administration during lactation

Precautions & Warnings

• Avoidance of initiation during exacerbation
• Use in asthma patients
• Asthma-related adverse events
• Paradoxical Bronchospasm
• Increased reporting of pneumonia in COPD patients
• Corticosteroids effects
• Reduction in growth velocity for paediatric patients

Use in Special Populations

• Potential reduction in growth velocity for paediatric patients

Overdose Effects

• Signs and symptoms of Salmeterol overdose
• Signs and symptoms of Fluticasone Propionate overdose

Therapeutic Class

• Long-acting selective β-adrenoceptor stimulants
• Respiratory corticosteroids

Storage Conditions

• Instructions for storage and handling

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