Flumetol (25 mcg+125 mcg)/puff (Inhaler)

Indications

• Regular treatment of asthma
• Combination product for inadequately controlled asthma
• Controlled inhaled corticosteroids and long-acting β2-agonist

Pharmacology

• Salmeterol as selective beta-2 agonist
• Fluticasone Propionate as a corticosteroid with glucocorticoid activity
• Improvement of lung function and prevention of asthma exacerbations

Dosage

• Adult dosage for inhaler
• Children dosage for inhaler
• Adult and adolescent dosage for inhalation capsule
• Pediatric dosage for inhalation capsule
• Dosage for Maxhaler in adults and adolescents
• Dosage for Maxhaler in children
• Dosage for COPD patients

Administration

• Proper use of Inhaler for effective medication delivery
• Importance of regular and correct inhaler usage
• Cleaning instructions for the Inhaler

Interaction

• Avoidance of non-selective and selective β-blockers in asthma patients
• Care with co-administration of strong CYP3A4 inhibitors

Contraindications

• Hypersensitivity to salmeterol xinafoate or fluticasone propionate
• Not for primary treatment of status asthmaticus or acute asthma episodes

Side Effects

• Tremor, palpitations, headache as Salmeterol side effects
• Hoarseness, candidiasis, hypersensitivity as Fluticasone Propionate side effects

Pregnancy & Lactation

• Consideration of benefit-risk in pregnancy and lactation
• Insufficient human data for pregnant and lactating mothers

Precautions & Warnings

• Avoidance during exacerbation or unstable asthma
• Vigilance for asthma-related adverse events
• Paradoxical Bronchospasm
• Increased risk of pneumonia in COPD patients
• Adverse effects of inhaled corticosteroids
• Impact on growth velocity in pediatric patients

Use in Special Populations

• Potential reduction in growth velocity in pediatric patients

Overdose Effects

• Signs and symptoms of Salmeterol overdose
• Temporary suppression of adrenal function with Fluticasone Propionate overdose

Therapeutic Class

• Long-acting selective β-adrenoceptor stimulants
• Respiratory corticosteroids

Storage Conditions

• Avoid puncturing or incinerating pressurized canister
• Storage below 30°C and away from direct sunlight

Related Brands

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