Protide 50 mcg+250 mcg (Inhalation Capsule)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Indications

  • Regular treatment of asthma
  • Combination product for inadequate control with inhaled corticosteroids
  • Combination product for adequately controlled patients

Pharmacology

  • Selective long-acting beta-2 agonist (salmeterol xinafoate)
  • Corticosteroid with glucocorticoid activity (fluticasone propionate)
  • Topical effect on the lungs without systematic effects

Dosage

  • Different dosages for adults, adolescents, and children
  • Inhaler and inhalation capsule options
  • Maxhaler for asthma and COPD

Administration

  • Instructions for effective inhaler use
  • Cleaning instructions for the inhaler

Interaction

  • Avoidance of non-selective and selective β-blockers
  • Care needed with strong CYP3A4 inhibitors

Contraindications

  • Hypersensitivity to salmeterol xinafoate or fluticasone propionate
  • Primary treatment of acute episodes of asthma

Side Effects

  • Transient side effects of beta-2-agonist treatment
  • Hoarseness and candidiasis as side effects of corticosteroid

Pregnancy & Lactation

  • Consideration of benefit-risk in pregnancy and lactation
  • Insufficient human experience with the product

Precautions & Warnings

  • Avoid initiation during exacerbation or unstable asthma
  • Vigilance for serious asthma-related adverse events
  • Possible paradoxical bronchospasm
  • Increased reporting of pneumonia in COPD patients

Use in Special Populations

  • Possibility of reduction in growth velocity in pediatric patients

Overdose Effects

  • Signs and symptoms of salmeterol and fluticasone overdose
  • Treatment of salmeterol overdose with appropriate beta-blocking agents

Therapeutic Class

  • Long-acting selective β-adrenoceptor stimulants
  • Respiratory corticosteroids

Storage Conditions

  • Pressurized canister storage precautions
  • Avoidance of direct sunlight or heat

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