Protide (25 mcg+250 mcg)/puff (Inhaler)

Indications

• regular treatment of asthma
• combination product use

Pharmacology

• selective beta-2 agonist
• corticosteroid with glucocorticoid activity
• protects against symptoms
• improves lung function
• prevents exacerbations

Dosage

• adult dosage
• adolescent dosage
• child dosage
• asthma inhalation capsule dosage
• COPD inhalation capsule dosage
• Maxhaler dosage
• Inhaler cleaning instructions

Administration

• proper inhaler use steps
• importance of regular use

Interaction

• avoidance of non-selective β-blockers
• caution with CYP3A4 inhibitors

Contraindications

• hypersensitivity history
• primary treatment of status asthmaticus

Side Effects

• pharmacological side effects of beta-2-agonist treatment
• adverse events associated with corticosteroid
• occurrence of known adverse events

Pregnancy & Lactation

• consideration of benefit-risk ratio in pregnancy
• limited human pregnancy/lactation data

Precautions & Warnings

• avoid initiation during exacerbation
• absence of relief for acute symptoms
• paradoxical bronchospasm occurrence
• vigilance for pneumonia in COPD patients
• possibility of systemic corticosteroid effects

Use in Special Populations

• potential impact on paediatric growth

Overdose Effects

• no human overdose data
• signs and symptoms of overdose
• treatment for Salmeterol overdose
• effects of Fluticasone Propionate overdose

Therapeutic Class

• long-acting selective β-adrenoceptor stimulants
• respiratory corticosteroids

Storage Conditions

• pressurised canister precautions
• avoidance of direct sunlight or heat
• storage temperature limits

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