Zymarin 0.5% (Ophthalmic Solution)
5 ml drop: ৳ 140.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Gatifloxacin |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- Bacterial conjunctivitis treatment
- Treatment of susceptible bacterial strains
- Aerobic Gram-Positive Bacteria susceptibility
- Aerobic Gram-Negative Bacteria susceptibility
Pharmacology
- Inhibition of DNA gyrase and topoisomerase IV
- Different mechanism of action from other antibiotics
- Cross-resistance observation between fluoroquinolones
- Multiple-step mutation resistance development
Dosage & Administration
- 0.3% eye drops recommended dosage regimen
- 0.5% eye drops dosage for patients 1 year of age or older
- Dosage for Days 1 and 2
- Dosage for Days 3 through 7
Interaction
- Elevation of plasma concentrations of theophylline
- Interference with caffeine metabolism
- Enhanced effects of oral anticoagulant warfarin
- Transient elevations in serum creatinine with cyclosporine concomitant use
Contraindications
- Hypersensitivity to Gatifloxacin or other quinolones
- Components hypersensitivity
- Avoid subconjunctival injection
- Avoid introduction into the anterior chamber of the eye
Side Effects
- Reported adverse events like conjunctival irritation
- Increased lacrimation
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy if benefit justifies potential risk to the fetus
- Excretion in human milk unknown
- Caution during nursing
Precautions & Warnings
- Advice on not wearing contact lenses with bacterial conjunctivitis signs and symptoms
- Avoid contaminating the applicator tip
Use in Special Populations
- No observed overall differences in safety or effectiveness between elderly and younger patients
Overdose Effects
- Unlikely to threaten life with overdose
Therapeutic Class
- Ophthalmic antibacterial drugs
Storage Conditions
- Store in cool, dry place away from light
- Keep out of reach of children