Zymarin 0.5% (Ophthalmic Solution)

5 ml drop: ৳ 140.00

Medicine Details

Category	Details
Generic	Gatifloxacin
Company	Eskayef pharmaceuticals ltd
Also available as	Zymar 03 eye drop

Indications

Bacterial conjunctivitis treatment
Treatment of susceptible bacterial strains
Aerobic Gram-Positive Bacteria susceptibility
Aerobic Gram-Negative Bacteria susceptibility

Pharmacology

Inhibition of DNA gyrase and topoisomerase IV
Different mechanism of action from other antibiotics
Cross-resistance observation between fluoroquinolones
Multiple-step mutation resistance development

Dosage & Administration

0.3% eye drops recommended dosage regimen
0.5% eye drops dosage for patients 1 year of age or older
Dosage for Days 1 and 2
Dosage for Days 3 through 7

Interaction

Elevation of plasma concentrations of theophylline
Interference with caffeine metabolism
Enhanced effects of oral anticoagulant warfarin
Transient elevations in serum creatinine with cyclosporine concomitant use

Contraindications

Hypersensitivity to Gatifloxacin or other quinolones
Components hypersensitivity
Avoid subconjunctival injection
Avoid introduction into the anterior chamber of the eye

Side Effects

Reported adverse events like conjunctival irritation
Increased lacrimation

Pregnancy & Lactation

Pregnancy Category C
Use during pregnancy if benefit justifies potential risk to the fetus
Excretion in human milk unknown
Caution during nursing

Precautions & Warnings

Advice on not wearing contact lenses with bacterial conjunctivitis signs and symptoms
Avoid contaminating the applicator tip

Use in Special Populations

No observed overall differences in safety or effectiveness between elderly and younger patients

Overdose Effects

Unlikely to threaten life with overdose

Therapeutic Class

Ophthalmic antibacterial drugs

Storage Conditions

Store in cool, dry place away from light
Keep out of reach of children

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