Kmi 320 mg (Tablet)
Unit Price: ৳ 65.00 (6's pack: ৳ 390.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Gemifloxacin |
| Company | Kemiko pharmaceuticals ltd |
Indications
- Treatment of acute bacterial exacerbation of chronic bronchitis
- Treatment of community-acquired pneumonia
Pharmacology
- Bactericidal action
- Inhibition of DNA synthesis
- Rapid absorption after oral administration
Dosage & Administration
- 320 mg once daily for 5 days for acute bacterial exacerbation of chronic bronchitis
- 320 mg tablet daily for 5-7 days for community-acquired pneumonia
Interaction
- Reduced absorption with aluminium or magnesium containing antacids and iron salts
- No significant interactions with omeprazole, theophylline, digoxin, warfarin, or oral contraceptives
Contraindications
- Hypersensitivity to Gemifloxacin and other quinolones
- Tendon damage with fluoroquinolones
- Not for use in children under 18 years of age
Side Effects
- Abdominal pain
- Diarrhea
- Headache
- Nausea
- Rash
- Vomiting
- Dizziness
- Insomnia
- Urticaria
- Pruritis
- Maculopapular erythmatous skin rash
Pregnancy & Lactation
- Not for use in pregnant or lactating women
- Safety and efficacy not established in pregnant or lactating women
Precautions & Warnings
- Dosage alteration for severe renal function impairment
- Maintenance of adequate hydration
- Possible dizziness
- Tendinitis and tendon ruptures
- Caution in patients predisposed to QTc interval prolongation or taking QTc interval prolonging medications
- Caution in patients with epilepsy
Use in Special Populations
- No dose adjustment in mild/moderate renal impairment
- Dosage guidelines for severe renal dysfunction
- No requirement for dose adjustment in hepatic impairment
- No dose adjustment for elderly patients
Overdose Effects
- No specific antidote known
- Symptomatic treatment
- Maintain hydration
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children