Exor 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Esomeprazole
Company Orion pharma ltd
Also available as
Exor 20 mg capsule Exor 40 mg injection

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • First single optical isomer of proton pump inhibitor
  • Provides better acid control than racemic proton pump inhibitors
  • Absorption peak plasma levels at approximately 1.5 hours
  • Systemic bioavailability is approximately 90%
  • 97% bound to plasma proteins
  • Extensively metabolized in the liver
  • Plasma elimination half-life of approximately 1-1.5 hours

Dosage

  • Oral dosage form
  • 20 mg or 40 mg Once Daily for 4-8 Weeks for erosive esophagitis
  • 20 mg Once Daily for maintenance of erosive esophagitis
  • 20 mg Once Daily for symptomatic GERD
  • Triple Therapy for Helicobacter pylori eradication
  • 20-80 mg once daily for Zollinger-Ellison Syndrome
  • 20-40 mg once daily for Acid-related Dyspepsia
  • 20 mg once daily for 2-4 weeks for Duodenal ulcer
  • 20-40 mg once daily for 4-8 weeks for Gastric ulcer
  • Dosage for IV Injection or IV infusion in adult and pediatric patients
  • 80 mg for risk reduction of rebleeding of Gastric or Duodenal Ulcers in adults

Administration

  • Tablet or capsule to be swallowed whole and taken one hour before a meal
  • Oral Suspension instructions
  • IV Injection preparation and administration

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • Unlikely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
  • Potential interference with CYP2C19
  • Not clinically significant interactions with specific drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Instructions for patients
  • Use in Special Populations including paediatric, geriatric, hepatic and renal insufficiency

Overdose Effects

  • Signs of acute toxicity in rats
  • No reports of overdose with Exor
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions about Exor 40 mg Capsule

  • Exor 40 mg Capsule is a proton pump inhibitor (PPI)
  • Multiple uses including treating GERD, ulcers, and conditions involving excess stomach acid
  • Common side effects
  • Safety during pregnancy and breastfeeding
  • Onset of action and quick tips

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