Exor 40 mg (Capsule (Enteric Coated))
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Orion pharma ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms and other symptoms associated with GERD
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
- Zollinger-Ellison Syndrome
- Acid related Dyspepsia
- Duodenal & Gastric ulcer
Pharmacology
- Proton pump inhibitor
- Suppresses gastric acid secretion
- First single optical isomer of proton pump inhibitor
- Provides better acid control than racemic proton pump inhibitors
- Absorption peak plasma levels at approximately 1.5 hours
- Systemic bioavailability is approximately 90%
- 97% bound to plasma proteins
- Extensively metabolized in the liver
- Plasma elimination half-life of approximately 1-1.5 hours
Dosage
- Oral dosage form
- 20 mg or 40 mg Once Daily for 4-8 Weeks for erosive esophagitis
- 20 mg Once Daily for maintenance of erosive esophagitis
- 20 mg Once Daily for symptomatic GERD
- Triple Therapy for Helicobacter pylori eradication
- 20-80 mg once daily for Zollinger-Ellison Syndrome
- 20-40 mg once daily for Acid-related Dyspepsia
- 20 mg once daily for 2-4 weeks for Duodenal ulcer
- 20-40 mg once daily for 4-8 weeks for Gastric ulcer
- Dosage for IV Injection or IV infusion in adult and pediatric patients
- 80 mg for risk reduction of rebleeding of Gastric or Duodenal Ulcers in adults
Administration
- Tablet or capsule to be swallowed whole and taken one hour before a meal
- Oral Suspension instructions
- IV Injection preparation and administration
Interaction
- Extensively metabolized in the liver by CYP2C19 and CYP3A4
- Unlikely to inhibit CYPs 1A2, 2A6, 2C9, 2D6, 2E1 and 3A4
- Potential interference with CYP2C19
- Not clinically significant interactions with specific drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects in animal studies
- Excretion in milk not studied
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Instructions for patients
- Use in Special Populations including paediatric, geriatric, hepatic and renal insufficiency
Overdose Effects
- Signs of acute toxicity in rats
- No reports of overdose with Exor
- No specific antidote known
- Treatment should be symptomatic and supportive
Storage Conditions
- Store at a temperature not exceeding 30°C
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image
Common Questions about Exor 40 mg Capsule
- Exor 40 mg Capsule is a proton pump inhibitor (PPI)
- Multiple uses including treating GERD, ulcers, and conditions involving excess stomach acid
- Common side effects
- Safety during pregnancy and breastfeeding
- Onset of action and quick tips