Comprid XR 60 mg (Tablet (Extended Release))

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Gliclazide
Company Square pharmaceuticals plc
Also available as
Comprid 80 mg tablet Comprid xr 30 mg tablet

Title

  • Comprid XR 60 mg Tablet

Categories

  • Diabetes medication
  • Oral antidiabetic medicine
  • Sulphonylurea group
  • Modified release preparation
  • Film-coated tablet
  • Therapeutic Class: Sulfonylureas

Description

  • Reduces blood sugar levels in adults with type 2 diabetes Mellitus
  • Stimulates insulin release from pancreatic cells
  • Decreases hepatic glucose output
  • Usual initial dose is 40 to 80 mg daily
  • Can be increased up to 320 mg daily in divided doses when needed
  • Recommended daily dose is one to four tablets (maximum 120 mg) in a single intake at breakfast time
  • Tablet to be taken with a glass of water at breakfast time
  • Swallow whole tablet without chewing or crushing
  • Always eat a meal after taking the tablet
  • Interacts with other medicines like sulphonamides, clarithromycin, beta-blockers, ACE-inhibitors, miconazole, fluconazole, monoamine oxidase inhibitors, phenylbutazone, metformin, GLP-1 receptor agonists, insulin, etc.
  • Can be taken with food and non-alcoholic drinks
  • Avoid drinking alcohol while on medication
  • May impair concentration and reaction if blood sugar is too low or too high
  • Contains lactose
  • Not recommended while breastfeeding
  • Not recommended for use during pregnancy
  • Regular monitoring of blood and urine sugar levels is necessary
  • Symptoms of low blood sugar and high blood sugar
  • Storage below 30°C
  • Dispose of unused medicine properly

Indications

  • Reduces blood sugar levels in adults with type 2 diabetes Mellitus when diet, exercise, and weight loss are ineffective

Mode of action

  • Stimulates insulin release from pancreatic cells
  • Decreases hepatic glucose output

Dosage administration

  • Usual initial dose is 40 to 80 mg daily
  • Can be increased up to 320 mg daily in divided doses when needed
  • Recommended daily dose is one to four tablets (maximum 120 mg) in a single intake at breakfast time
  • Take tablet with a glass of water at breakfast time
  • Swallow whole tablet without chewing or crushing
  • Always eat a meal after taking the tablet
  • Consult doctor for dose adjustments due to changes in lifestyle, stress, or blood sugar control

Interaction

  • Strengthened effect:
    • Oral antidiabetics
    • GLP-1 receptor agonists
    • Insulin
    • Sulphonamides
    • Clarithromycin
    • Beta-blockers
    • ACE-inhibitors
    • Miconazole
    • Fluconazole
    • Monoamine oxidase inhibitors
    • Phenylbutazone
  • Weakened effect:
    • Chlorpromazine
    • Corticosteroids
    • Intravenous salbutamol
    • Ritodrine
    • Terbutaline
    • Danazol
    • St John's Wort- Hypericum perforatum- preparations
  • Other interaction info:
    • May increase effects of warfarin
    • Consult doctor before starting another medicinal product
    • Avoid drinking alcohol
    • May impair driving and machine usage if blood sugar is too low or too high

Contraindications

  • Allergic to gliclazide or related medicines
  • Insulin-dependent diabetes (type 1)
  • Diabetic ketoacidosis, pre-coma, or coma
  • Severe kidney or liver disease
  • Taking medicines for fungal infections
  • Breastfeeding

Side effects

  • Low blood sugar (hypoglycaemia)
  • Abnormal liver function
  • Skin reactions like rash, redness, itching, hives
  • Decrease in blood cells causing paleness, prolonged bleeding, etc.
  • Digestive disorders like abdominal pain, nausea, vomiting
  • Temporary vision impairment
  • Reporting side effects is recommended

Pregnancy lactation

  • Not recommended for use during pregnancy
  • Not recommended while breastfeeding

Precautions warnings

  • Regular monitoring of blood and urine sugar levels
  • Increased risk of low blood sugar in the first few weeks of treatment
  • Symptoms of low blood sugar and high blood sugar
  • Avoid missed or irregular meals, malnutrition, and alcohol consumption
  • Consult doctor in case of hormone-induced disorders, kidney or liver function impairment
  • Not recommended for use in children

Storage conditions

  • Store below 30°C
  • Dispose of unused medicine properly

Chemical structure

  • Molecular formula: C15H21N3O3S
  • Chemical structure image url: https://medex.com.bd/storage/res/g-res-523-gliclazide-chemical-structure-txBrG0haplJbTTRCKheC.svg

Common questions

  • What is Comprid XR 60 mg XR Tablet?: Medication for managing type 2 diabetes by lowering blood sugar levels
  • What happens if I take Comprid XR 60 mg XR Tablet without eating?: Dosage is tied to meals, should be skipped if a meal is missed
  • What if I missed a dose of Comprid XR 60 mg XR Tablet?: Take the missed dose as soon as remembered, but don't take two doses together
  • How long does the effect of Comprid XR 60 mg XR Tablet last?: The effect lasts for an average duration of 24 hours
  • Are there any pregnancy warnings for Comprid XR 60 mg XR Tablet?: Not recommended for pregnant women
  • General Instructions: Take as directed by the doctor, monitor blood sugar levels regularly, carry sugary candy to treat hypoglycemia, and avoid missed meals

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