Limpet 4 mg (Tablet)

Unit Price: ৳ 11.00 (2 x 14: ৳ 308.00)
Strip Price: ৳ 154.00

Medicine Details

Category Details
Generic Glimepiride
Company Drug international ltd
Also available as
Limpet 1 mg tablet Limpet 2 mg tablet Limpet 3 mg tablet

Indications

  • Lowering blood glucose in noninsulin dependent diabetes mellitus (NIDDM)
  • Adjunct to diet and exercise for diabetes control
  • Combination use with metformin
  • Combination use with insulin for diabetes control

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Stimulates insulin release from pancreatic beta cells
  • Improves beta cell sensitivity to glucose stimulus
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin

Dosage

  • Initial dose based on regular blood and urine glucose check
  • Gradual dose titration based on monitoring
  • Usual initial dose of 1 mg once daily
  • Dose range for well controlled diabetes: 1 to 4 mg daily

Administration

  • Tablet must be swallowed with sufficient liquid

Interaction

  • Potentiating drugs include ACE inhibitors, fluconazole, chloramphenicol, and more
  • Attenuating drugs include barbiturates, corticosteroids, diazoxide, and more
  • Possible interactions with beta-receptor blockers, clonidine, and reserpine

Contraindications

  • Not for insulin dependent diabetes mellitus
  • Not for diabetic ketoacidosis or diabetic coma
  • Contraindicated in patients hypersensitive to sulfonylureas or sulfonamides
  • Not for patients with severe hepatic dysfunction or renal impairment

Side Effects

  • Hypoglycemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Not to be taken during pregnancy, changeover to insulin necessary
  • Breastfeeding not recommended

Precautions & Warnings

  • Initial weeks may have increased risk of hypoglycemia
  • Necessity for careful monitoring and dosage adjustments
  • Prompt control of hypoglycemia with immediate carbohydrate intake

Overdose Effects

  • Overdosage can produce hypoglycemia
  • Treatment with oral glucose for mild symptoms
  • Severe cases require hospitalization and rapid IV glucose injection

Therapeutic Class

  • Sulfonylureas

Storage Conditions

  • Store below 30°C
  • Keep away from light and out of reach of children

Related Brands