SB-Glim 1 mg (Tablet)

Unit Price: ৳ 6.00 (60's pack: ৳ 360.00)

Medicine Details

Indications

  • Adjunct to diet and exercise for type II diabetes mellitus
  • Use in combination with metformin or insulin
  • Potential for hypoglycaemia with insulin combination
  • Lowering blood glucose levels

Pharmacology

  • Sulfonylurea antidiabetic agent
  • Stimulates insulin release from pancreatic beta cells
  • Reduces basal hepatic glucose production
  • Increases peripheral tissue sensitivity to insulin
  • Improves glucose uptake

Dosage

  • Regulated by desired blood sugar level
  • Initial dose of 1mg once daily
  • Gradual dose titration based on glucose monitoring
  • Dose range of 1-4mg daily
  • Single daily dose with substantial breakfast or main meal

Administration

  • Tablet must be swallowed with sufficient liquid

Interaction

  • Potential interactions with various drugs
  • Potentiating and attenuating effects on hypoglycaemic action
  • Additive effects with other oral blood sugar lowering agents
  • Masking of hypoglycaemic attack symptoms

Contraindications

  • Not suitable for insulin dependent diabetes mellitus
  • Not for diabetic ketoacidosis or coma
  • Hypersensitivity to glimepiride or sulfonylureas
  • Severe hepatic or renal dysfunction
  • Not for dialysis patients

Side Effects

  • Hypoglycaemia
  • Temporary visual impairment
  • Nausea
  • Vomiting
  • Diarrhoea
  • Abdominal pain
  • Urticaria
  • Fall in blood pressure

Pregnancy & Lactation

  • Not to be taken during pregnancy
  • Changeover to insulin is necessary
  • Harmful effects on breastfeeding child
  • Not to be taken by breastfeeding women

Precautions & Warnings

  • Increased risk of hypoglycaemia in initial weeks
  • Carbohydrate intake for prompt control of hypoglycaemia

Overdose Effects

  • Potential for hypoglycaemia
  • Mild symptoms treated with oral glucose and dosage adjustments
  • Severe reactions constitute medical emergencies

Therapeutic Class

  • Sulfonylureas

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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