SB-Glim 4 mg (Tablet)

Unit Price: ৳ 15.00 (50's pack: ৳ 750.00)

Medicine Details

Indications

  • Adjunct to diet and exercise to lower blood glucose in noninsulin-dependent diabetes mellitus (NIDDM)
  • Use in combination with metformin or insulin for adequate glycaemic control

Pharmacology

Stimulates insulin release from pancreatic beta cells, reduces hepatic glucose production, improves peripheral tissue sensitivity to insulin

Dosage

  • Initial Dose: 1 mg once daily
  • Usual Dose Range: 1 to 4 mg daily
  • Timing and Distribution: Decided by physician based on patient's lifestyle
  • Secondary Dosage Adjustment: Considered as control of diabetes improves
  • Changeover from Other Oral Antidiabetics: Initial dose of 1 mg

Administration

Tablets must be swallowed with sufficient liquid

Interaction

  • Potentiate the Hypoglycaemic Action:
    • ACE inhibitors
    • Cyclophosphamide
    • Fluconazole
  • Attenuate the Hypoglycaemic Action:
    • Acetazolamide
    • Barbiturates
    • Calcium channel blockers

Contraindications

  • Insulin dependent diabetes mellitus
  • Diabetic ketoacidosis
  • Hypersensitivity to Glimepiride or sulfonylureas
  • Severe hepatic dysfunction
  • Severe impairment of renal function

Side Effects

  • Hypoglycaemia
  • Nausea
  • Temporary visual impairment
  • Abdominal pain

Pregnancy & Lactation

Not suitable for use during pregnancy or breastfeeding

Precautions & Warnings

Increased risk of hypoglycaemia in initial weeks of treatment, necessitates careful monitoring

Overdose Effects

Can produce hypoglycaemia, requiring aggressive treatment with glucose and close monitoring

Therapeutic Class

Sulfonylureas

Storage Conditions

Store below 30°C, away from light and out of reach of children

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