Maxima 40 mg/vial (IV Injection)
40 mg vial: ৳ 90.27
Medicine Details
Category | Details |
---|---|
Generic | Esomeprazole |
Company | Acme laboratories ltd |
Also available as |
Indications
- Relief from chronic heartburn symptoms
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection
- Treatment of Zollinger-Ellison Syndrome
- Treatment of acid-related Dyspepsia
- Treatment of Duodenal and Gastric ulcers
Pharmacology
- Proton pump inhibitor
- Suppression of gastric acid secretion
- Inhibition of H+/K+-ATPase
- Better acid control than racemic proton pump inhibitors
- Enteric-coated pellet formulation
- Peak plasma levels at approximately 1.5 hours
- Metabolized in the liver by CYP enzyme system
- Excretion in urine and faeces
Dosage
- Oral dosage form
- IV Injection or IV infusion
- Specific dosage for healing of erosive esophagitis
- Specific dosage for symptomatic GERD
- Specific dosage for Helicobacter pylori eradication
- Specific dosage for Zollinger-Ellison Syndrome
- Specific dosage for Acid-related Dyspepsia
- Specific dosage for Duodenal and Gastric ulcers
- Dosage for pediatric and adult patients
- Dosage for risk reduction of rebleeding of ulcers
Administration
- Tablet or capsule administration
- Oral suspension administration
- IV Injection solution preparation
- IV Injection administration
- Instructions for administering through nasogastric or gastric tube
Interaction
- Metabolism by CYP2C19 and CYP3A4
- Inhibition of CYP2C19
- Potential interference with drug absorption
- Lack of clinically significant interactions with certain drugs
Contraindications
- Known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- No teratogenic effects in animal studies
- Excretion in milk not studied
- Discontinuation of breast-feeding if essential
Precautions & Warnings
- Symptomatic response does not preclude the presence of gastric malignancy
- Instructions for patients
- Use of antacids while taking the product
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- No overall differences in safety and efficacy in geriatric use
- No dosage adjustment for mild to moderate hepatic insufficiency
- No alteration of Pharmacokinetics in renal impairment
Overdose Effects
- Lethal to rats at high doses
- Symptomatic and supportive treatment recommended
Storage Conditions
- Temperature not exceeding 30°C
- Dry place
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
- Chemical Structure Image
Common Questions about Maxima 40 mg/vial Injection
- Definition of Maxima 40 mg/vial Injection
- Uses of Maxima 40 mg/vial Injection
- Side effects of Maxima 40 mg/vial Injection
- Safety during pregnancy and breastfeeding
- Onset of action and quick tips