Maxpro 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.00 (6 x 10: ৳ 540.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Esomeprazole
Company Renata limited
Also available as
Maxpro 20 mg tablet Maxpro 20 mg capsule Maxpro 40 mg capsule Maxpro 40 mg injection

Indications

  • Relief from chronic heartburn symptoms
  • Relief from other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of Acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Inhibition of H+/K+-ATPase
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours
  • Extensive metabolism in the liver
  • Low plasma elimination half-life

Dosage

  • Oral Dosage Form:
    • Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
    • Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
    • Symptomatic GERD: 20 mg Once Daily for 4 Weeks
    • Helicobacter Pylori Eradication: 40 mg Once Daily for 10 Days
  • IV Injection or IV Infusion:
    • Adult Patients (≥18 years): 20 mg or 40 mg once daily
    • Pediatric Patients: 10 mg or 20 mg once daily based on body weight
    • Risk reduction of rebleeding of Gastric or Duodenal Ulcers: 80 mg initial dose followed by continuous infusion

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension should be taken with water and consumed immediately
  • IV Injection should be administered intravenously over a period of at least 3 minutes

Interaction

  • Extensive metabolism in the liver
  • Potential interference with CYP2C19
  • No clinically significant interactions with specific drugs

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion in milk not studied
  • Breast-feeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules
  • Antacids may be used while taking the medication

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy observed in geriatric patients
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics in patients with renal impairment

Overdose Effects

  • Lethal to rats at high doses
  • Reduced motor activity
  • Respiratory frequency changes
  • Tremor and ataxia

Storage Conditions

  • Store at temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Maxpro 40 mg Tablet

  • What is Maxpro 40 mg Tablet?: Proton pump inhibitor used for various gastrointestinal conditions
  • What is Maxpro 40 mg Tablet used for?: Relief from heartburn, healing of erosive esophagitis, and prevention of recurrence
  • What are the side effects of Maxpro 40 mg Tablet?: Headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth
  • Can I take Maxpro 40 mg Tablet if I am pregnant or breastfeeding?: Consult a doctor regarding risks and benefits
  • How long does it take for Maxpro 40 mg Tablet to work?: Usually within a few hours of ingestion
  • Quick Tips:
    • Well-tolerated medicine providing long-term relief
    • Avoid eating late at night or before bedtime
    • Seek medical attention for specific symptoms

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