Maxpro 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 14: ৳ 980.00)
Strip Price: ৳ 98.00

Medicine Details

Category Details
Generic Esomeprazole
Company Renata limited
Also available as
Maxpro 20 mg tablet Maxpro 40 mg tablet Maxpro 40 mg capsule Maxpro 40 mg injection

Indications

  • To relieve chronic heartburn symptoms and other symptoms associated with GERD
  • For the healing of erosive esophagitis
  • For maintenance of healing of erosive esophagitis
  • In combination with amoxicillin and clarithromycin for eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Suppresses gastric acid secretion
  • Inhibition of H+/K+-ATPase
  • Optical isomer of proton pump inhibitor
  • Peak plasma levels occur at approximately 1.5 hours
  • Metabolized by cytochrome P450 enzyme system
  • Plasma protein binding is constant over a certain concentration range
  • Plasma elimination half-life is approximately 1-1.5 hours

Dosage

  • 20 mg or 40 mg Once Daily for Healing of Erosive Esophagitis
  • 20 mg Once Daily for Maintenance of Healing of Erosive Esophagitis
  • 20 mg Once Daily for Symptomatic GERD
  • Triple Therapy for Helicobacter Pylori eradication
  • Dosing range for Zollinger-Ellison Syndrome
  • Dosing range for Acid-related Dyspepsia
  • 20 mg Once Daily for Duodenal ulcer and Gastric ulcer

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension to be taken with water according to specific instructions
  • IV Injection or IV infusion for specific conditions and patient groups

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with certain CYP enzymes expected
  • Potential interference with CYP2C19 substrates
  • Possibility of interfering with absorption of drugs dependent on gastric pH
  • Increased plasma levels observed with certain drug combinations

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied

Precautions & Warnings

  • Symptomatic response does not rule out gastric malignancy
  • Specific instructions for patients with difficulty swallowing capsules
  • Use of antacids alongside the product

Use in Special Populations

  • Paediatric Use safety and effectiveness not established
  • No overall differences in safety and efficacy observed between elderly and younger individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Renal insufficiency expected to not alter pharmacokinetics significantly

Overdose Effects

  • Acute toxicity symptoms in animal studies
  • No specific antidote known
  • Treatment should be symptomatic and supportive

Storage Conditions

  • Store at temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Commonly Asked Questions

  • Description of Maxpro 20 mg Capsule
  • Uses of Maxpro 20 mg Capsule
  • Side effects of Maxpro 20 mg Capsule
  • Use in pregnancy and breastfeeding
  • Time to onset of action for Maxpro 20 mg Capsule
  • Quick Tips on Maxpro 20 mg Capsule usage

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