Maxpro 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.00 (10 x 10: ৳ 1,000.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Esomeprazole
Company Renata limited
Also available as
Maxpro 20 mg tablet Maxpro 40 mg tablet Maxpro 20 mg capsule Maxpro 40 mg injection

Indications

  • Relief from chronic heartburn symptoms and other symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Duodenal and Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase in the gastric parietal cell
  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Peak plasma levels occur at approximately 1.5 hours after oral administration
  • Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
  • Plasma elimination half-life of approximately 1–1.5 hours

Dosage

  • Oral dosage form
  • IV Injection or IV infusion
  • Dosage varies based on indication
  • Dosage for adults and pediatric patients

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension instructions
  • IV Injection preparation and administration

Interactions

  • Metabolized by CYP2C19 and CYP3A4
  • Potentially interferes with the absorption of certain drugs
  • No clinically relevant interactions with specific drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • General patient information
  • Use with antacids
  • Instructions for patients with difficulty swallowing capsules
  • Caution for individuals with difficulty swallowing

Use in Special Populations

  • Paediatric use not established
  • No overall differences in safety and efficacy observed between the elderly and younger individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in patients with renal impairment

Overdose Effects

  • Signs of acute toxicity in overdose cases
  • No specific antidote known
  • Treatment should be symptomatic and supportive
  • Possibility of multiple drug ingestion

Storage Conditions

  • Store at temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure illustration

Common Questions about Maxpro 40 mg Capsule

  • Definition and usage
  • Multiple uses including treating GERD, ulcers, and excessive stomach acid
  • Common side effects
  • Use during pregnancy and breastfeeding
  • Duration for onset of action
  • Quick tips for use

Related Brands