Neptor 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 8.50 (8 x 10: ৳ 680.00)
Strip Price: ৳ 85.00

Medicine Details

Category Details
Generic Esomeprazole
Company Sandoz a novartis division
Also available as
Neptor 40 mg capsule

Product Title

  • Neptor 20 mg Capsule

Categories

  • Medicine
  • Pharmaceutical

Description

  • A proton pump inhibitor used to relieve chronic heartburn
  • Treats symptoms associated with GERD
  • Heals erosive esophagitis
  • Maintains healing of erosive esophagitis
  • Eradicates Helicobacter pylori infection
  • Manages Zollinger-Ellison Syndrome
  • Addresses acid-related Dyspepsia
  • Heals duodenal and gastric ulcers

Color Options

  • N/A

Dimensions

  • N/A

Function

  • Relief from chronic heartburn
  • Erosive esophagitis healing
  • Eradication of Helicobacter pylori infection
  • Symptomatic treatment for Zollinger-Ellison Syndrome
  • Management of Duodenal and Gastric ulcers

Materials

  • Esomeprazole magnesium

Technical Specifications

  • Enteric-coated pellet formulation of esomeprazole magnesium
  • Absorption peak plasma levels at approximately 1.5 hours
  • 97% plasma protein binding
  • Cytochrome P450 (CYP) enzyme system metabolism
  • Plasma elimination half-life of approximately 1-1.5 hours

Design Elements

  • Enteric-coated capsules
  • Oral suspension
  • IV Injection or IV infusion

Usability Features

  • Swallow whole and taken one hour before a meal for tablet or capsule
  • Administered through a nasogastric or gastric tube for oral suspension
  • IV Injection administration over a period of at least 3 minutes

Dosage Options

  • 20 mg or 40 mg Once Daily for 4-8 Weeks for Healing of Erosive Esophagitis
  • 20 mg Once Daily for Maintenance of Healing of Erosive Esophagitis
  • 20 mg Once Daily for Symptomatic GERD
  • 40 mg Once Daily for Helicobacter Pylori eradication
  • 20-80 mg Once Daily for Zollinger-Ellison Syndrome
  • 20-40 mg Once Daily for Acid-related Dyspepsia
  • 20 mg Once Daily for 2-4 weeks for Duodenal ulcer
  • 20-40 mg Once Daily for 4-8 weeks for Gastric ulcer
  • IV Injection dosage for Adult and Pediatric patients
  • 80 mg for Risk reduction of rebleeding of Gastric or Duodenal Ulcers following therapeutic endoscopy in adults

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Duodenal & Gastric ulcers

Administration

  • Swallowed whole and taken one hour before a meal for tablet or capsule
  • Oral suspension administration with water, nasogastric or gastric tube
  • IV injection with reconstituted solution for injection

Interaction

  • Extensively metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with certain drugs metabolized by specific CYP enzymes
  • Potential interference with CYP2C19 enzyme
  • Co-administration with clarithromycin increases plasma levels of Neptor and 14-hydroxyclarithromycin

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion of esomeprazole in milk not studied
  • Discontinuation of breastfeeding if essential use of esomeprazole

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Guidelines for patients on capsule administration
  • Allowance for antacid use while taking Neptor
  • No established safety and effectiveness in pediatric patients
  • No significant differences in safety and efficacy between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics in patients with renal impairment

Use in Special Populations

  • No established safety and effectiveness in pediatric patients
  • No significant differences in safety and efficacy between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics in patients with renal impairment

Overdose Effects

  • No reports of overdose with Neptor
  • No specific antidote known
  • Symptomatic and supportive treatment recommended
  • Consideration of multiple drug ingestion

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • Dry place
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions

  • What is Neptor 20 mg Capsule?
  • What is Neptor 20 mg Capsule used for?
  • What are the side effects of Neptor 20 mg Capsule?
  • Can I take Neptor 20 mg Capsule if I am pregnant or breastfeeding?
  • How long does it take for Neptor 20 mg Capsule to work?
  • Quick Tips for Neptor 20 mg Capsule

Animal studies

  • No teratogenic effects

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