Quiet XR 50 mg (Tablet (Extended Release))
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quetiapine fumarate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of acute and chronic psychoses
- Treatment of schizophrenia
- Bipolar disorder treatment for manic episodes
- Bipolar disorder treatment for depressive episodes
- Maintenance treatment of bipolar I disorder
- Combination therapy with mood stabilizers
Pharmacology
- Belongs to dibenzothiazepine derivatives
- Antagonist at multiple neurotransmitter receptors
- Antagonism of dopamine and serotonin receptors
- Antagonism of histamine and adrenergic receptors
Dosage & Administration
- Twice daily administration
- Can be administered with or without food
- Initial dosage titration for first four days
- Flexible dosage range for clinical response
- Adjusted dose for different episodes and disorders
Interaction
- Caution with medicines causing electrolyte imbalance
- Caution with medications increasing QT interval
- Potential interactions with thioridazine, carbamazepine, phenytoin
Contraindications
- Contra-indicated in hypersensitive patients
Side Effects
- Common adverse reactions include somnolence, dizziness, dry mouth
- Elevations in serum triglyceride and cholesterol levels
- Decrease in HDL cholesterol, weight gain
- Potential for extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy during human pregnancy not established
- Use only if benefits outweigh potential risks
- Avoid breast-feeding while taking the medication
Precautions & Warnings
- Increased risk of suicide-related events
- Caution in patients with known cardiovascular or cerebrovascular disease
- Caution in patients with history of seizures or tardive dyskinesia
- Potential neuroleptic malignant syndrome
- Caution with patients having family history of QT prolongation
- Risk of neutropenia, hyperglycemia, and diabetes mellitus
Use in Special Populations
- Caution in elderly patients due to reduced plasma clearance
- Not indicated for children and adolescents below 18 years of age
Overdose Effects
- Survival reported in acute overdoses of up to 30 grams
- No specific antidote available
- Intensive care procedures recommended
- Treat refractory hypotension with appropriate measures
- Close medical supervision and monitoring required
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of reach of children
- Do not use after expiry date
- Store in a cool, dry place away from light