Opton 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Esomeprazole
Company Beximco pharmaceuticals ltd
Also available as
Opton 20 mg tablet Opton 20 mg capsule Opton 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Treatment of Zollinger-Ellison Syndrome
  • Management of acid-related Dyspepsia
  • Healing of Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Specific inhibition of the H+/K+-ATPase
  • Better acid control than racemic proton pump inhibitors
  • Enteric-coated pellet formulation
  • Peak plasma levels at approximately 1.5 hours after oral administration
  • Metabolized in the liver by the cytochrome P450 (CYP) enzyme system
  • Extensively metabolized forming hydroxy and desmethyl metabolites
  • Plasma elimination half-life of approximately 1-1.5 hours

Dosage

  • Oral dosage form for various conditions
  • Specific dosages for different indications
  • IV Injection and IV infusion dosages
  • Weight-based dosages for pediatric patients
  • Dosage for risk reduction of rebleeding of Gastric or Duodenal Ulcers

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral suspension administration instructions
  • IV Injection preparation and administration
  • IV infusion administration guidelines

Interaction

  • Metabolized in the liver by CYP2C19 and CYP3A4
  • No clinically relevant interactions with specific CYP enzymes expected
  • Potential interference with the absorption of certain drugs due to gastric pH changes

Contraindications

  • Known hypersensitivity to any of the formulation

Side Effects

  • Frequently occurring adverse events including headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies show no teratogenic effects
  • Excretion in milk not studied, discontinuation of breastfeeding recommended if essential

Precautions & Warnings

  • Symptomatic response to therapy does not preclude the presence of gastric malignancy
  • Special instructions for patients with difficulty swallowing capsules

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No observed differences in safety and efficacy between elderly and younger individuals
  • No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
  • Unaltered pharmacokinetics in patients with renal impairment

Overdose Effects

  • Acute toxicity signs in animal studies
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Store at a temperature not exceeding 30°C, protect from light and moisture

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image URL

Common Questions about Opton 40 mg Tablet

  • Explanation of Opton 40 mg Tablet as a proton pump inhibitor
  • Various uses of Opton 40 mg Tablet
  • Common side effects of Opton 40 mg Tablet
  • Recommendations for pregnant or breastfeeding individuals
  • Typical timeframe for Opton 40 mg Tablet to take effect
  • Quick tips for Opton 40 mg Tablet usage

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