Progut 40 mg (Capsule (Enteric Coated))

Unit Price: ৳ 11.00 (6 x 10: ৳ 660.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Esomeprazole
Company Popular pharmaceuticals ltd
Also available as
Progut 20 mg tablet Progut 20 mg capsule Progut 40 mg injection

Indications

  • Relieves chronic heartburn symptoms
  • Treats symptoms associated with GERD
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
  • Treatment of Zollinger-Ellison Syndrome
  • Treatment of acid-related Dyspepsia
  • Treatment of Duodenal & Gastric ulcers

Pharmacology

  • Proton pump inhibitor
  • Suppresses gastric acid secretion
  • Enhances acid control
  • Enteric-coated pellet formulation
  • Absorption peak at approximately 1.5 hours
  • Distribution with 97% plasma protein binding
  • Extensively metabolized in the liver
  • Excretion of less than 1% unchanged in the urine

Dosage

  • Oral dosage form available
  • Different dosages for specific conditions
  • IV Injection or IV infusion for certain conditions
  • Guidelines for adult and pediatric patients

Administration

  • Tablet or capsule should be swallowed whole
  • Oral suspension preparation and administration
  • IV solution preparation and administration

Interaction

  • Extensively metabolized in the liver
  • No clinically relevant interactions with certain drugs
  • Potential interference with CYP2C19 and CYP3A4
  • Possible impact on absorption of specific drugs

Contraindications

  • Contraindicated in patients with known hypersensitivity

Side Effects

  • Frequently occurring adverse events include headache, diarrhea, nausea, flatulence, abdominal pain, constipation, dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects observed in animal studies
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not exclude gastric malignancy
  • Specific guidance for patients with difficulty swallowing capsules
  • Antacids may be used alongside

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety and efficacy for elderly individuals
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • No alteration in pharmacokinetics expected in renal impairment

Overdose Effects

  • Lethal dose observed in animal studies
  • Major signs of acute toxicity include reduced motor activity, respiratory changes, tremor, and convulsions
  • No specific antidote known

Storage Conditions

  • Recommended storage temperature not exceeding 30°C
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S

Common Questions about Progut 40 mg Capsule

  • Proton pump inhibitor reducing stomach acid production
  • Uses include treating GERD, ulcers, and excessive stomach acid conditions
  • Common side effects and effective relief
  • Caution during pregnancy and breastfeeding
  • Effective within a few hours of ingestion
  • Quick Tips provided for patient guidance

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