Indica-G 110 mcg+50 mcg (Inhalation Capsule)
Unit Price: ৳ 50.00 (3 x 10: ৳ 1,500.00)
Strip Price: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Indacaterol glycopyrronium |
| Company | Acme laboratories ltd |
Indications
- Long-term maintenance bronchodilator treatment
- Chronic obstructive pulmonary disease (COPD)
- Chronic bronchitis
- Emphysema
- Once-daily usage
- Not for acute episodes of bronchospasm
- Not for asthma
Composition
- Indacaterol 110 mcg as Indacaterol Maleate INN (Micronized)
- Glycopyrronium 50 mcg as Glycopyrronium Bromide BP (Micronized)
Pharmacology
- Delivery through oral inhalation
- Combined action of Glycopyrronium and Indacaterol
- Stimulation of intracellular adenyl cyclase
- Relaxation of bronchial smooth muscle
- Inhibition of release of mediators of immediate hypersensitivity
- Long-acting muscarinic antagonist
- Inhibition of M3 receptor at the smooth muscle
- Bronchodilation
Dosage & Administration
- For adults (18 years or older)
- Maintenance treatment of COPD: 1 inhalation once daily
- Not for relief of acute bronchospasm
- Not for children and adolescents
- Use in patients with renal impairment
- Use in patients with hepatic impairment
Interaction
- No specific interaction studies
- Caution with concomitant use of hypokalemic treatment
- Not recommended with β-adrenergic blockers, anticholinergics, or sympathomimetic agents
Contraindications
- Hypersensitivity to Glycopyrronium or Indacaterol
- Severe hypersensitivity to milk proteins
- LABA use in patients with asthma without long-term asthma control medication
Side Effects
- Cardiovascular effects
- Ocular disorders
- Urinary retention
- Gastrointestinal disorders
- Dry mouth
- Cough
- Immediate hypersensitivity reactions
- Hypokalemia
- Hyperglycemia
- Headache
- Nervousness
- Insomnia
- Muscle spasms
- Fatigue
- Malaise
- Tremor
Pregnancy & Lactation
- Pregnancy category C
- Use during pregnancy if expected benefit justifies potential risk to the foetus
- Consideration for breast-feeding women if expected benefit to the woman is greater than any possible risk to the infant
Precautions & Warnings
- Increased risk of serious asthma-related events with LABA monotherapy
- Avoid initiation in acutely deteriorating COPD or asthma
- Caution with cardiovascular disorders
- Caution with convulsive disorders, thyrotoxicosis, diabetes mellitus, and ketoacidosis
- Potential worsening of narrow-angle glaucoma
- Potential worsening of urinary retention
- Alert for hypokalemia and hyperglycemia
Overdose Effects
- Exaggerated effects typical of β2-adrenergic stimulants
- Tachycardia
- Tremor
- Palpitations
- Headache
- Nausea
- Vomiting
- Drowsiness
- Ventricular arrhythmias
- Metabolic acidosis
- Hypokalemia
- Hyperglycaemia
- Anticholinergic effects
- Increased intraocular pressure
- Obstipation
- Difficulties in voiding
- Supportive and symptomatic treatment
Therapeutic Class
- Combined bronchodilators
Storage Conditions
- Avoid storage in direct sunlight or heat
- Store in a cool & dry place
- Keep away from eyes
- Keep out of reach of children
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