Indapa-Plus 2 mg+1.25 mg (Tablet)
Unit Price: ৳ 6.05 (2 x 10: ৳ 121.00)
Strip Price: ৳ 60.50
Medicine Details
| Category | Details |
|---|---|
| Generic | Perindopril indapamide |
| Company | Drug international ltd |
| Also available as |
Indications
- Treatment of essential hypertension
Pharmacology
- Nonsulphydryl ACE inhibitor
- Rapid hydrolysis to active metabolite
- Inhibition of ACE activity
- Decreased vasoconstriction
- Increased plasma renin activity
- Interference with bradykinin degradation
- Diuretic action
Dosage & Administration
- 1-2 tablets per day
- Preferably taken in the morning before a meal
- Dose adjustment for renal insufficiency
Interaction
- Potentiation with antihypertensive & antipsychotic drugs
- Reduction of antihypertensive effect by NSAIDs
- Risk of hyperkalemia with ARB and Potassium Sparing diuretics
Contraindications
- Hypersensitivity to perindopril/ indapamide
- Hypersensitivity to any other ACE inhibitor
Side Effects
- Nausea
- Vomiting
- Dyspepsia
- Diarrhea
- Constipation
- Headache
- Dizziness
- Sleep disturbance
- Asthenia
- Dry mouth
- Hypotension
- Dry cough
- Angioedema
- Rash
Pregnancy & Lactation
- Not recommended in pregnancy
- Not recommended for breastfeeding mothers
Precautions & Warnings
- Use with caution in renal impairment
- Use with caution in renal artery stenosis
- Use with caution in heart failure
- Use with caution in gout
- Use with caution in diabetes
- Use with caution in liver cirrhosis
- Use with caution in elderly patients
- Use with caution in atherosclerosis
- Use with caution in idiopathic or hereditary angioedema
Overdose Effects
- Hypotension
- Nausea
- Vomiting
- Cramps
- Dizziness
- Sleepiness
- Mental confusion
- Oliguria
- Anuria
- Salt and water disturbances
- Gastric lavage may be used
- Administration of activated charcoal may be used
- Fluid and electrolyte balance monitoring
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Store below 30°C