Somazole 20 mg (Capsule (Enteric Coated))

Unit Price: ৳ 7.00 (10 x 10: ৳ 700.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Esomeprazole
Company Ad din pharmaceuticals ltd
Also available as
Somazole 40 mg capsule

Indications

  • Relief from chronic heartburn symptoms
  • Erosive esophagitis healing
  • Maintenance of erosive esophagitis healing
  • Helicobacter pylori infection eradication
  • Zollinger-Ellison Syndrome treatment
  • Acid-related Dyspepsia relief
  • Duodenal and Gastric ulcer treatment

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Inhibition of H+/K+-ATPase
  • Optical isomer of proton pump inhibitor
  • Enteric-coated pellet formulation
  • Metabolized in the liver by cytochrome P450 enzyme system
  • Plasma protein binding
  • Excretion in urine and faeces
  • Combination therapy with antimicrobials

Dosage

  • Oral dosage form
  • IV Injection and IV infusion
  • Various doses for different indications
  • Special dosages for pediatric patients
  • Duration of treatment for different conditions

Administration

  • Swallowing whole tablet or capsule
  • Preparation and administration of oral suspension
  • Preparation of IV injection
  • Administration before meals

Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Potential interference with drug absorption
  • No clinically significant interactions with certain drugs

Contraindications

  • Hypersensitivity to any of the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Excretion of esomeprazole in milk not studied

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Administration at least one hour before meals
  • Information for patients regarding swallowing capsules
  • Use of antacids while taking Somazole

Use in Special Populations

  • Safety and effectiveness in pediatric patients not established
  • No overall differences in safety and efficacy in geriatric patients
  • No dosage adjustment recommended for mild to moderate hepatic insufficiency
  • Pharmacokinetics not expected to be altered in renal impairment patients

Overdose Effects

  • Lethal dose in rats
  • Signs of acute toxicity
  • Symptomatic and supportive treatment

Storage Conditions

  • Temperature not exceeding 30°C
  • Dry place
  • Protection from light and moisture

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions

  • Multiple uses of Somazole 20 mg Capsule
  • Common side effects
  • Safety during pregnancy and breastfeeding
  • Onset of action
  • Quick Tips for usage

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