Sompraz 40 mg (Tablet (Enteric Coated))

Unit Price: ৳ 9.50 (5 x 10: ৳ 475.00)
Strip Price: ৳ 95.00

Medicine Details

Category Details
Generic Esomeprazole
Company Sun pharmaceutical bangladesh ltd
Also available as
Sompraz 20 mg tablet Sompraz 20 mg capsule Sompraz 40 mg capsule

Title

  • Sompraz 40 mg Tablet

Categories

  • Medicine
  • Gastroenterology

Description

  • Proton pump inhibitor for treating chronic heartburn and GERD symptoms
  • Indicated for healing erosive esophagitis and maintaining healing
  • Used in combination with antibiotics for Helicobacter pylori eradication
  • Effective for Zollinger-Ellison Syndrome, Acid-related Dyspepsia, and ulcers
  • Various dosage forms for different patient populations
  • Pharmacology includes gastric acid secretion suppression and absorption details
  • Approved interaction precautions and contraindications
  • List of common side effects and precautions during pregnancy and lactation
  • Information on administration and storage conditions
  • Chemical structure details and frequently asked questions

Dimensions

  • Tablet: 40 mg

Color Options

  • White

Function

  • Reduces gastric acid production
  • Heals erosive esophagitis
  • Eradicates Helicobacter pylori

Dosage Form

  • Oral tablet
  • Oral suspension
  • IV injection
  • IV infusion

Dosage Strengths

  • 20 mg
  • 40 mg
  • 80 mg

Dosage Duration

  • Daily for 4-8 weeks for healing erosive esophagitis
  • 20 mg once daily for maintenance of healing
  • 10-day triple therapy for Helicobacter pylori eradication
  • 20-40 mg once daily for Zollinger-Ellison Syndrome

Administration

  • Tablet and capsule should be taken one hour before a meal
  • Instructions for administering oral suspension and IV injection

Pharmacokinetics

  • Peak plasma levels at approximately 1.5 hours
  • Metabolism by CYP enzymes
  • Elimination half-life of approximately 1-1.5 hours

Drug Interaction

  • Metabolism by CYP2C19 and CYP3A4
  • Potential interference with CYP2C19 substrate absorption
  • No clinically significant interactions reported with several drugs

Contraindications

  • Known hypersensitivity to the formulation

Side Effects

  • Headache
  • Diarrhoea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • No teratogenic effects in animal studies
  • Recommendation to discontinue breastfeeding if essential

Precautions & Warnings

  • Symptomatic response does not rule out gastric malignancy
  • Patient instructions for swallowing capsules
  • Use of antacids while taking the medicine

Special Populations

  • No established safety and effectiveness in paediatric patients
  • No overall differences observed in the elderly
  • No dosage adjustment in mild to moderate hepatic insufficiency
  • Expected lack of alteration in renal impairment

Overdose Effects

  • Toxicity signs in animal studies
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Temperature not exceeding 30°C
  • Protect from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Image: https://medex.com.bd/storage/res/g-res-433-esomeprazole-chemical-structure-Tj2Jfp1VmPkRjNXznKqC.svg

Commonly Asked Questions

  • Usage and action explanation
  • Side effects and pregnancy concerns
  • Time to efficacy and quick tips for use

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