Esozyme 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Esomeprazole |
| Company | Cosmic pharma ltd |
| Also available as |
Indications
- Relief from chronic heartburn symptoms and other symptoms associated with GERD
- Healing of erosive esophagitis
- Maintenance of healing of erosive esophagitis
- Eradication of Helicobacter pylori infection in patients with duodenal ulcer disease
- Zollinger-Ellison Syndrome
- Acid related Dyspepsia
- Duodenal & Gastric ulcers
Pharmacology
- Proton pump inhibitor that suppresses gastric acid secretion
- Single optical isomer providing better acid control
- Absorbed after oral administration
- Extensively metabolized in the liver
- Plasma elimination half-life of approximately 1–1.5 hours
Dosage
- 20 mg or 40 mg Once Daily for 4-8 Weeks for healing of erosive esophagitis
- 20 mg Once Daily for maintenance of healing of erosive esophagitis
- 20 mg Once Daily for symptomatic GERD
- 40 mg Once Daily for Helicobacter Pylori eradication
- 20-80 mg once daily for Zollinger-Ellison Syndrome
Administration
- Tablet or capsule should be swallowed whole and taken one hour before a meal
- Oral Suspension should be mixed with water and consumed within 30 minutes
- IV Injection or IV infusion to be administered as per specific protocols
Interaction
- Extensively metabolized in the liver by CYP2C19 and CYP3A4
- No clinically relevant interactions with specific drugs metabolized by certain CYP enzymes expected
- Potential interference with CYP2C19
- Combination Therapy with Clarithromycin can influence plasma levels
Contraindications
- Contraindicated in patients with known hypersensitivity to any of the formulation
Side Effects
- Headache
- Diarrhoea
- Nausea
- Flatulence
- Abdominal pain
- Constipation
- Dry mouth
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Animal studies revealing no teratogenic effects
- Excretion in milk not studied
- Breast-feeding should be discontinued if essential
Precautions & Warnings
- Symptomatic response to therapy does not preclude the presence of gastric malignancy
- Specific information for patients on capsule consumption
- Use of antacids
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- No overall differences in safety and efficacy observed between the elderly and younger individuals
- No dosage adjustment recommended for patients with mild to moderate hepatic insufficiency
Overdose Effects
- Reported acute toxicity in rats
- No specific antidote known
- Treatment should be symptomatic and supportive
Storage Conditions
- Store at a temperature not exceeding 30°C in a dry place
- Protect from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C17H19N3O3S
Common Questions about Esozyme 20 mg Tablet
- Proton pump inhibitor used to treat GERD, ulcers, and other conditions involving excessive stomach acid
- Common side effects include headaches, diarrhea, nausea, gas, stomach pain, constipation, and dry mouth
- Pregnant or breastfeeding individuals should consult a doctor before use
- Starts to work within a few hours of taking it
Miscellaneous
- No reports of overdose with Esozyme
- No change in pharmacokinetic profile of Esozyme with specific co-administered drugs