Delpino 5 mg (Tablet)
Unit Price: ৳ 25.00 (1 x 10: ৳ 250.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ivabradine |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Symptomatic treatment of chronic stable angina pectoris in coronary artery disease patients with normal sinus rhythm
- In patients unable to tolerate or with a contra-indication to the use of beta-blockers
- In combination with beta-blockers in patients inadequately controlled with an optimal beta-blocker dose and whose heart rate is > 60 bpm
Pharmacology
- Pure heart rate lowering agent
- Selective and specific inhibition of the cardiac pacemaker I f current
- Regulates heart rate by decreasing cardiac workload and oxygen consumption
- Prolongs diastole allowing increased perfusion of coronary arteries and increased oxygen supply to the heart
Dosage & Administration
- Usual recommended starting dose of 5 mg twice daily
- May be increased after 3-4 weeks to 7.5 mg twice daily
- Usual dose is 1 tablet in the morning and 1 tablet in the evening
- Consider lower starting dose for elderly patients
- No dose adjustment in patients with renal insufficiency and creatinine clearance above 15ml/min
Interaction
- QT wave prolonging medicinal products not recommended
- Close cardiac monitoring needed for concomitant use with QT wave prolonging medicinal products
Contraindications
- Resting heart rate below 60 bpm before treatment
- Cardiogenic shock
- Acute myocardial infarction
- Severe hypotension (<90/50 mmHg)
- Pacemaker dependent
- Unstable angina
- Combination with strong cytochrome P-450 3A4 inhibitors
Side Effects
- Visual symptoms
- Blurred vision
- Bradycardia
- Headaches
- Dizziness
Pregnancy & Lactation
- Contra-indicated during pregnancy
- Contra-indicated during breast-feeding
Precautions & Warnings
- Mild to moderate hypotension
- Atrial fibrillation
- Patients with congenital QT syndrome or treated with QT wave prolonging medicinal products
- Moderate hepatic insufficiency
- Severe renal insufficiency
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children